• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Clinical Application of the Meridian Grid Theory: A Signal-Energy Integration Model Based on the Five Phases Interpromotion and Restraint, Meridian Tropism of Chinese Materia Medica, and Five-Tone Therapy

Corresponding author: WangZhize, 15603181218@sina.cn
DOI: 10.12201/bmr.202603.00013
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Abstract: Based on the previously proposed "Meridian Grid Theory," this paper further explores the interaction mechanisms among meridians and applies this theoretical framework to explain clinical practices in traditional Chinese medicine, including the interpromotion and restraint among the Five Phases, meridian tropism of Chinese materia medica, the principles of hemostasis, and Five-Tone therapy. By analyzing modern research on the viscera-manifestation relationships of meridians, quantitative studies on the theory of meridian tropism, the molecular mechanisms of acupuncture hemostasis, and the biophysical foundations of Five-Tone therapy, this paper demonstrates the fundamental nature of meridians as dynamic signal networks. Using Sijunzi Decoction and Xiaochaihu Decoction as examples, it elucidates the "signal synergy" mechanism in formula compatibility. This study aims to provide a unified underlying theoretical framework for understanding clinical therapeutic principles in traditional Chinese medicine.

    Key words: Meridian Grid Theory; signal network; interpromotion and restraint among the Five Phases; meridian tropism of Chinese materia medica; Five-Tone therapy; hemostasis mechanism; formula explanation

    Submit time: 14 April 2026

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  • ID Submit time Number Download
    1 2026-03-06

    10.12201/bmr.202603.00013V1

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WangZhize. Clinical Application of the Meridian Grid Theory: A Signal-Energy Integration Model Based on the Five Phases Interpromotion and Restraint, Meridian Tropism of Chinese Materia Medica, and Five-Tone Therapy. 2026. biomedRxiv.202603.00013

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