Prevention and Treatment of Postoperative Recurrence of Colonic Adenoma and Adenoma-Carcinoma Transformation: Insights from the Theory of “Yin-Yang Self-Harmony Leading to Spontaneous Recovery”Chen Lang1? AN ZHENxiang1、2

Corresponding author: ANZHENxiang, 407206115@qq.com

DOI: 10.12201/bmr.202604.00114

•  

  Abstract: Colorectal cancer, as one of the most common malignant tumors of the digestive system, poses an escalating public health risk due to its continuously increasing global incidence. Colonic adenomatous polyps are currently recognized as the most common precancerous lesions of colorectal cancer, and blocking the “adenoma-carcinoma transformation” has become a key link in primary prevention of colorectal cancer. Although endoscopic resection is available in Western medicine, the high postoperative recurrence rate remains a major clinical challenge, and Western medicine lacks systematic intervention strategies. The theory of “Yin-Yang self-harmony leading to spontaneous recovery,” originating from the Treatise on Cold Damage, emphasizes that the pathogenesis of postoperative recurrence of colonic adenoma and “adenoma-carcinoma transformation” lies essentially in “insufficient Yin-Yang self-harmony.” By reinforcing healthy Qi and eliminating pathogenic factors to assist Yin-Yang self-harmony, and by regulating the overall internal environment of the body, the body’s self-healing potential can be restored. This article systematically reviews the theoretical connotation of “Yin-Yang self-harmony” and its association with the pathogenesis of colonic adenoma, and explores prevention and treatment strategies based on this theory in combination with clinical case studies.

  Key words: Yin-Yang self-harmony; Colonic adenoma; Colorectal cancer; Adenoma-carcinoma transformation

  Submit time: 14 April 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• XIE QiaoJie, Xie si pei. Clinical and ultrasound characteristics of thyroid follicular adenoma and follicular carcinoma. 2026. doi: 10.12201/bmr.202602.00031

  Zhao Ruiguo, Zhou Lurong, Wang Ning▲. Discussing the pathogenesis and treatment of colorectal cancer with Iron Death on the basis of “health and evil all originate from yin and yang”.. 2025. doi: 10.12201/bmr.202505.00043

  chen chao, tao yuan. Treatment of Colonic Polyps Based on the Theory of Yang Deficiency and Yin Stagnation. 2026. doi: 10.12201/bmr.202602.00086

  YU Yunfeng, YANG Xinyu, HU Gang, Tang Xudong, YOU Yunge. Based on the Theory of Yin and Yang to Explore the Mechanism of Autophagy in Ulcerative Colitis and Chinese Medicine Intervention Strategies. 2025. doi: 10.12201/bmr.202501.00001

  Xu Lu-zhou. Exploring the Pathogenesis and Treatment Strategies of Gastric Inflammation-Cancer Transformation Based on the Theory of Where There is Lingering Masses, There Must Be Latent Yang. 2025. doi: 10.12201/bmr.202511.00044

  ZHENG Jian yu. From Yin-Yang and Five Elements Theory to Dynamical System Cybernetics: Modern Mathematical Reconstruction of Traditional Chinese Medicine Theory. 2026. doi: 10.12201/bmr.202603.00075

  Wang Xia, Qian Rui, Ma Di. Discussion on the treatment of subacute thyroiditis based on the theory of yin and yang of internal meridian. 2025. doi: 10.12201/bmr.202503.00083

  ZHENG Jian Yu. Reconstruction of the Dynamical Model of Traditional Chinese Medicine's "Yin - Yang Balance" Based on Lyapunov Stability Theory. 2026. doi: 10.12201/bmr.202603.00076

  Experience of the treatment of insomnia from the theory of ‘Harmony and Stability’. 2024. doi: 10.12201/bmr.202407.00028

  He Xiao Yuan, Ning Mei. Research Progress on the Relationship between Insulin Resistance and the Occurrence and Development of Colorectal Cancer and Intervention Measures Chen Yunxiu 1, He Xiaoyuan 1, Ning Mei 2*. 2026. doi: 10.12201/bmr.202601.00062

• ID	Submit time	Number	Download
  1	2026-03-27	10.12201/bmr.202604.00114V1	Download

• Public  Anonymous  To author only Submit Comments