Current Status of Helicobacter pylori Infection, Nutritional Status and Risk Factors Analysis in Preschool Children in Dongguan Area

DOI: 10.12201/bmr.202604.00038

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  Abstract: Objective To investigate the infection rate, nutritional status and risk factors of Helicobacter pylori (Hp) in preschool children aged 3–6 years in Dongguan, and to provide evidence for the prevention and control of Hp infection in children.Methods A total of 2086 preschool children aged 3–6 years with gastrointestinal symptoms and complete data who received medical treatment from January 2023 to December 2024 were enrolled. All children underwent 13C-urea breath test. Relevant risk factors for Hp infection were analyzed using questionnaire survey, physical examination and hemoglobin detection. Results Among the 2086 children, 1053 were Hp-positive, with an infection rate of 50.5%. Statistically significant differences (P<0.05) were found between Hp-positive and Hp-negative groups in age, body weight, BMI, hemoglobin level, shared tablewa基金项目：东莞市社会发展科技项目（20231800938272）通讯作者：段高羊，电子信箱：duangaoyang52@126.comre, hygiene habits and family history of gastrointestinal diseases. Multivariate Logistic regression analysis showed that shared tableware, poor hygiene habits and family history of gastrointestinal diseases were independent risk factors for Hp infection.Conclusion The Hp infection rate is high in preschool children with gastrointestinal symptoms in Dongguan, and Hp infection may affect their nutritional status. Shared tableware, poor hygiene habits and family history of gastrointestinal diseases are the main risk factors. Targeted prevention and control interventions should be carried out.

  Key words: Helicobacter pylori; Preschool children; ; Nutritional status; Risk factors

  Submit time: 7 April 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2026-03-08	10.12201/bmr.202604.00038V1	Download

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