通讯作者: 段高羊, duangaoyang52@126.com

DOI：10.12201/bmr.202604.00038

Current Status of Helicobacter pylori Infection, Nutritional Status and Risk Factors Analysis in Preschool Children in Dongguan Area

• 摘要：目的 探讨东莞地区 3～6 岁学龄前儿童幽门螺杆菌(Hp)感染率、营养状况及危险因素,为儿童 Hp 感染防控提供依据。方法 选取 2023 年 1 月 —2024 年 12 月就诊、有消化道症状且资料完整的 3～6 岁学龄前儿童 2086 例,行 13C - 尿素呼气试验。通过问卷调查、体格测量及血红蛋白检测,分析 Hp 感染相关危险因素。结果 2086 例儿童中 Hp 阳性 1053 例,感染率 50.5%。Hp 阳性与阴性组在年龄、体质量、BMI、血红蛋白、共用餐具、卫生习惯、家庭成员胃肠道疾病史等方面差异均有统计学意义(P＜0.05)。多因素 Logistic 回归显示,共用餐具、不良卫生习惯、家庭成员胃肠道疾病史为 Hp 感染独立危险因素。结论 东莞地区有消化道症状的学龄前儿童 Hp 感染率高,且可影响营养状况,共用餐具、不良卫生习惯、家庭成员胃肠道疾病史是 Hp感染的主要危险因素,应针对性开展防控干预。

  关键词： 幽门螺杆菌; 学龄前儿童; 营养状况; 危险因素; 

   

  Abstract: Objective To investigate the infection rate, nutritional status and risk factors of Helicobacter pylori (Hp) in preschool children aged 3–6 years in Dongguan, and to provide evidence for the prevention and control of Hp infection in children.Methods A total of 2086 preschool children aged 3–6 years with gastrointestinal symptoms and complete data who received medical treatment from January 2023 to December 2024 were enrolled. All children underwent 13C-urea breath test. Relevant risk factors for Hp infection were analyzed using questionnaire survey, physical examination and hemoglobin detection. Results Among the 2086 children, 1053 were Hp-positive, with an infection rate of 50.5%. Statistically significant differences (P<0.05) were found between Hp-positive and Hp-negative groups in age, body weight, BMI, hemoglobin level, shared tablewa基金项目：东莞市社会发展科技项目（20231800938272）通讯作者：段高羊，电子信箱：duangaoyang52@126.comre, hygiene habits and family history of gastrointestinal diseases. Multivariate Logistic regression analysis showed that shared tableware, poor hygiene habits and family history of gastrointestinal diseases were independent risk factors for Hp infection.Conclusion The Hp infection rate is high in preschool children with gastrointestinal symptoms in Dongguan, and Hp infection may affect their nutritional status. Shared tableware, poor hygiene habits and family history of gastrointestinal diseases are the main risk factors. Targeted prevention and control interventions should be carried out.

  Key words: Helicobacter pylori; Preschool children; ; Nutritional status; Risk factors

  提交时间：2026-04-07

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2026-03-08	10.12201/bmr.202604.00038V1	下载

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