Research Progress on Clinical Efficacy of Adjuvant Traditional Chinese Medicine Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Corresponding author: YANG Ruyi

DOI: 10.12201/bmr.202609.00010

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  Abstract: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a severe stage in the course of chronic obstructive pulmonary disease (COPD), characterized by a rapid worsening of respiratory symptoms, which significantly increases the risk of pulmonary function deterioration and mortality. In recent years, comprehensive intervention models that combine conventional Western medical treatment with commonly used Traditional Chinese Medicine (TCM) approaches? have drawn widespread attention. By systematically reviewing the relevant literature, Expand elaborately in turn from multiple dimensions including traditional Chinese medicine compound prescriptions, single Chinese medicinal herbs, traditional Chinese medicine injections, aerosol inhalation, as well as acupoint application, Chinese herbal fumigation and washing, acupuncture and moxibustion, scraping and cupping, dietary therapy and rehabilitation conditioning.this article aims to elucidate the clinical efficacy of such integrated Chinese and Western medicine strategies in the treatment of AECOPD. The findings demonstrate that TCM, serving as an adjuvant intervention, can significantly ameliorate clinical symptoms, optimize pulmonary function parameters, reduce serum concentrations of pro-inflammatory cytokines, regulate immune function, and promote the restoration of systemic immune homeostasis. On this basis, the limitations of existing studies are analyzed and future research directions are explored, with the goal of providing a reference for further in-depth investigations and clinical diagnostic and therapeutic practice for AECOPD.

  Key words: Acute Exacerbation of Chronic Obstructive Pulmonary Disease; Integrated Chinese and Western medicine treatment; Clinical efficacy; Review

  Submit time: 7 September 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2026-07-07	10.12201/bmr.202609.00010V1	Download

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