Advances in Exhaled Breath Condensate for Chronic Obstructive Pulmonary Disease

Corresponding author: Hongying Ma, fymahongying@nbu.edu.cn

DOI: 10.12201/bmr.202512.00038

•  

  Abstract: Chronic Obstructive Pulmonary Disease (COPD) is a common chronic respiratory disease characterized by persistent airflow limitation. With approximately 384 million patients worldwide, it imposes a substantial burden on society. Exhaled Breath Condensate (EBC) has emerged as a non-invasive, safe, and reproducible technique for collecting airway lining fluid, demonstrating significant potential for early screening of COPD, identification of inflammatory phenotypes, prediction of acute exacerbation risk, and evaluation of drug efficacy. This review systematically summarizes recent advancements in the research of various biomarkers in EBC and explores the prospects of integrating multi-omics technologies, aiming to provide a theoretical foundation for the clinical application of EBC in the precision diagnosis and treatment of COPD.

  Key words: COPD; EBC; Biomarker

  Submit time: 13 December 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• chenhongbo. Role of Novel Biomarkers in Early Detection of Chronic Kidney Disease. 2025. doi: 10.12201/bmr.202508.00003

  YanJu. Research progress of the serum biomarkers in neonatal hypoxic ischemic encephalopathy. 2025. doi: 10.12201/bmr.202502.00036

  ZHOU Jie, XIAO Wei. To explore the mechanism of oxidative stress and metabolic imbalance in COPD combined with type 2 diabetes from Qi-blood-body fluid theory. 2025. doi: 10.12201/bmr.202506.00039

  HANG Yu-jie, CHEN Kun, LIU Qian-yu, ZHANG Yu-bin, XU Liang, ZHANG Li-xue, BAI Jing-ya▲. Research progress of biomarkers for renal fibrosis. 2024. doi: 10.12201/bmr.202411.00072

  liuxue, lishujyu. Research progress related to biomarkers of acute Kidney injury. 2025. doi: 10.12201/bmr.202508.00028

  HuDndan, ZhangJinmei, ZhangXinru. Effect of Liuzijue Combined with External Treatment of Traditional Chinese Medicine on the efficacy and serum Inflammation levels in Stable COPD patients. 2025. doi: 10.12201/bmr.202505.00021

  Advances in Research on the Aggressive Nature of PitNETs Using Serological Markers in Combination with Imaging Biomarkers. 2025. doi: 10.12201/bmr.202508.00037

  sun jingjing, li xiaoling, wang manxia. . 2024. doi: 10.12201/bmr.202412.00078

  jiangyonghong. Research applications of blood markers in the diagnosis of insomnia disorders. 2025. doi: 10.12201/bmr.202502.00060

  张佳倩, Qi Ruonan, Ma Hongying, Liu Qingbing, Lv Dan. . 2025. doi: 10.12201/bmr.202511.00035

• ID	Submit time	Number	Download
  1	2025-11-16	10.12201/bmr.202512.00038V1	Download

• Public  Anonymous  To author only Submit Comments