• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Treatment of Sleep Disorder Secondary to Tinnitus of Kidney Essence Deficiency Pattern

Corresponding author: liziping, lzip_008@163.com
DOI: 10.12201/bmr.202604.00010
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Abstract:Objective: To observe the clinical efficacy of acupuncture combined with acupoint injection in the treatment of sleep disorder secondary to tinnitus with kidney essence deficiency pattern.Methods: A total of 60 patients with sleep disorder secondary to kidney essence deficiency pattern tinnitus were enrolled and randomly divided into the treatment group (acupuncture plus acupoint injection group) and the control group (sham acupuncture plus sham acupoint injection group), with 30 cases in each group. Both groups received treatment 3 times a week for 4 consecutive weeks. The changes of Tinnitus Evaluation Questionnaire (TEQ) score, Pittsburgh Sleep Quality Index (PSQI) score, Tinnitus Handicap Inventory (THI) score, and Traditional Chinese Medicine (TCM) syndrome score of patients in the two groups before and after treatment were observed, and the clinical efficacy of the two groups was compared.Results: After treatment, the TEQ, PSQI, THI scores and TCM syndrome scores of the two groups were significantly decreased compared with those before treatment (P<0.001), and the magnitude of score reduction in the treatment group was significantly greater than that in the control group (P<0.001). In terms of tinnitus efficacy, the total effective rate of the treatment group was 96.55%, which was significantly higher than 32.14% of the control group (?2=33.393, P<0.001). In terms of sleep disorder efficacy, the total effective rate of the treatment group was 96.55%, which was significantly higher than 25.00% of the control group (?2=39.176, P<0.001).Conclusion: Acupuncture combined with acupoint injection can significantly improve tinnitus symptoms and sleep quality, alleviate tinnitus-related functional disability, and ameliorate the TCM syndrome of kidney essence deficiency in patients with sleep disorder secondary to kidney essence deficiency pattern tinnitus. This therapy has stable efficacy and good safety, and is worthy of clinical promotion and application.

    Key words: tinnitus; sleep disorder; kidney essence deficiency; acupuncture; acupoint injection; randomized controlled trial

    Submit time: 2 April 2026

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  • ID Submit time Number Download
    1 2026-03-09

    10.12201/bmr.202604.00010V1

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laileixin, liziping. Treatment of Sleep Disorder Secondary to Tinnitus of Kidney Essence Deficiency Pattern. 2026. biomedRxiv.202604.00010

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