• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

The research progress on the association between MMP-9 and schizophrenia and its therapeutic prospects.

DOI: 10.12201/bmr.202407.00065
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Matrix metalloproteinase-9 (MMP-9) is a key zinc-dependent endoprotease that can degrade a variety of extracellular matrix proteins and participate in the regulation of normal physiological proces-ses (such as cell migration, tissue remodeling, etc.) and a variety of pathologi-cal process. Research shows that MMP-9 plays an important regulatory role in the occurrence and development of various diseases and has become a pote-ntial target for disease diagnosis and treatment. These findings have attracted scholars attention to the potential of MMP-9 as an immunological marker for schizophr-enia. This article aims to review the research progress on the relatio-nship between MMP-9 and schizophrenia at home and abroad in recent years, summarize the current r

    Key words: schizophrenia; matrix metalloproteinase-9; risk; inflammation

    Submit time: 28 July 2024

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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    1 2024-07-17

    bmr.202407.00065V1

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Xu Xiuying, Wu Wenting. The research progress on the association between MMP-9 and schizophrenia and its therapeutic prospects.. 2024. biomedRxiv.202407.00065

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