Research Progress of Wendan Decoction in the Treatment of Cardiovascular Diseases and Predictive Analysis of Its Quality Markers (Q-Marker)

Corresponding author: shihaijiao, 80670335@163.com

DOI: 10.12201/bmr.202610.00066

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  Abstract: Wendan Decoction is a classic renowned phlegm-resolving prescription in traditional Chinese medicine. Modern pharmacological studies have demonstrated that it exerts a variety of pharmacological effects, including lipid-lowering, antihypertensive and anti-inflammatory activities. Accordingly, it is widely applied in clinical practice for the treatment of coronary heart disease, arrhythmia, hypertension, insomnia and other disorders. This paper elaborates on the chemical constituents and pharmacological effects of Wendan Decoction, as well as the research advances in its treatment of cardiac diseases. Based on the five principles of Quality Marker (Q-Marker), this study identifies naringin, hesperidin, liquiritin, 6-gingerol, glycyrrhizic acid, nobiletin, neohesperidin, naringenin and hesperetin as the quality markers of Wendan Decoction. Nevertheless, subsequent experimental verification is still required to confirm their authenticity, so as to provide a theoretical basis for the quality evaluation of Wendan Decoction.

  Key words: Wendan Decoction; chemical components; pharmacological effects; clinical applications; quality markers (Q-Marker)

  Submit time: 28 October 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2026-08-20	10.12201/bmr.202610.00066V1	Download

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