Clinical observation on the treatment of malignant ascites of ovarian cancer (spleen and kidney yang deficiency type) with compound soap and thorn soup combined with calatin abdominal thermal perfusion

DOI: 10.12201/bmr.202604.00092

•  

  Abstract: : Objective: To observe the efficacy and safety of compound soap horn thorn soup combined with carplatin abdominal heat perfusion in the treatment of ovarian cancer malignant ascites (spleen and kidney yang deficiency type). Methods: 60 patients with ovarian cancer malignant ascites admitted to Changde First Traditional Chinese Medicine Hospital from November 2024 to November 2025 were randomly divided into treatment group and control group, 30 cases each. The control group was given single-drug carplatin abdominal heat perfusion chemotherapy, and the treatment group took the compound soap horn thorn soup on the basis of the control group. The total treatment efficiency, ascites relief efficiency, malignant ascites abdominal circumference, Karnofsky functional status scoring standard (KPS score), traditional Chinese medicine syndrome score, serum were recorded. CA125 protein level and the incidence of adverse reactions. Results: The difference between the abdominal circumference, KPS score, traditional Chinese medicine syndrome score and serum CA125 protein levels of the two groups of patients before treatment was not statistically significant (P>0.05); After treatment, the observation results of therapeutic effect showed that the total treatment efficiency of the treatment group was 90.0% (27/30) higher than that of the 73.33% (22/30) (P<0.05) in the photo group; the ascites relief efficiency of the treatment group was 86.66% (26/30) higher than that of 66.67% (20/30) (P<0.05) in the control group; the malignant ascites abdominal circumference of the two groups of patients after treatment decreased (P<0.05 ), the score of traditional Chinese medicine syndrome and KPS score decreased (P<0.05), and the serum CA125 protein level decreased (P<0.05). The treatment group was better than the control group. Safety observation results show that the incidence of adverse reactions in the two groups of patients is equivalent and the safety is high (P>0.05); Conclusion Compound soap horn thorn soup combined with carplatin abdominal heat perfusion to treat ovarian cancer malignant ascites (spleen and kidney yang deficiency type) can effectively reduce malignant ascites, control the progression of the disease, and improve the quality of survival of patients.

  Key words: : ovarian cancer; malignant ascites; compound soap horn thorn soup; carplatin; spleen and kidney yang deficiency type

  Submit time: 10 April 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• Zhang Aiqin. Zhang Aiqins Experience in Treating Ovarian Cancer after Operation and Chemotherapy. 2024. doi: 10.12201/bmr.202411.00016

  Chen Shuling, Chen Yun, Shu Qijin. Exploring the Medication Patterns of Patent Compound Therapy for Ovarian Cancer Based on Data Mining. 2025. doi: 10.12201/bmr.202510.00008

  胡芷晴, Pan Shan, Zhu Weili. Advances in Research on Ferroptosis Reversing Platinum Resistance in Ovarian Cancer. 2025. doi: 10.12201/bmr.202512.00070

  陈才月, xiangyong, chenzhaoxia, wangkewen, zhongwenliang. Discussion on the Treatment of Diabetic Cardiomyopathy from Spleen Yang Deficiency and Decline Based on the Theory of Yang Deficiency with Three Depletions Governed by the Spleen. 2026. doi: 10.12201/bmr.202603.00064

  XieChunhong, KangJia. Experience in Treating Premature Ovarian Insufficiency from the Perspective of Kidney, Liver, and Spleen. 2025. doi: 10.12201/bmr.202510.00036

  Li Yaping. Clinical Observation on the Treatment of Perimenopausal Insomnia of the Heart-kidney Disharmony Type by Regulating the Spirit and Nourishing the Heart Tang. 2024. doi: 10.12201/bmr.202408.00031

  Huang Hong Peng, Lin Yan Ting, Li Shou Jie, Chen Xiao Cong. Experience in treating malignant ascites from the method of removing blood stasis and resolving retained fluid. 2025. doi: 10.12201/bmr.202503.00011

  Lan Yisheng, Guo Anni, Zhan Airong. Observation on the Clinical Efficacy of Acupoint Application on Exercise Endurance and Cardiopulmonary Function in Patients with Stable COPD of Lung and Kidney Qi Deficiency Type. 2026. doi: 10.12201/bmr.202602.00020

  zhangming. One case of unicornuate uterus with residual horn uterus and right kidney absence complicated with ovarian endometriotic cyst. 2025. doi: 10.12201/bmr.202504.00055

  钟军, Wang Minggang, Mao Dewen, Liu Hao, Dong Jiamei, Liu Xingyu, Lin Xingzuo. Analysis of medication patterns of Traditional Chinese medicine for liver cancer with ascites based on data mining. 2026. doi: 10.12201/bmr.202603.00081

• ID	Submit time	Number	Download
  1	2026-03-16	10.12201/bmr.202604.00092V1	Download

• Public  Anonymous  To author only Submit Comments