Treatment of Active Ulcerative Colitis Based on the Theory of Wind, Dampness, Heat and Blood Stasis Accumulating in the Intestine, Damaging Intestinal Collaterals

DOI: 10.12201/bmr.202605.00058

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  Abstract: Professor Zhu Shenglang holds that the core pathogenesis of active ulcerative colitis is wind, dampness, heat and blood stasis accumulating in the intestine and damaging intestinal collaterals, which is a syndrome of root deficiency and branch excess. Spleen deficiency is the root cause, while wind, dampness, heat and blood stasis are the branch causes, and pathogenic wind is an important inducing factor. He establishes clearing heat and resolving dampness, dispelling wind and calming collaterals, and harmonizing qi and blood as the core therapeutic methods for acute attack. He has created the empirical prescription Hongteng Changan Decoction, which closely targets the pathogenesis, and is flexibly modified in clinical practice. It has shown remarkable efficacy in clinically controlling acute attacks and relieving symptoms such as mucopurulent bloody stool, abdominal pain and diarrhea. This article systematically summarizes from the aspects of pathogenesis understanding, syndrome differentiation characteristics, therapeutic methods and prescriptions, and modification features.

  Key words: Ulcerative Colitis; Active Stage; Clearing Heat and Resolving Dampness; Dispelling Wind and Calming Collaterals; Hongteng Changan Decoction

  Submit time: 17 May 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2026-05-03	10.12201/bmr.202605.00058V1	Download

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