Analysis of the Diagnosis and Treatment Strategies for Sj?grens Syndrome Based on the Theory of

Corresponding author: wangshenzhi, 361979636@qq.com

DOI: 10.12201/bmr.202601.00017

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  Abstract: : Primary Sj?grens syndrome (pSS) is a chronic inflammatory autoimmune disease characterized by lymphocyte proliferation and progressive exocrine gland damage. Its main clinical manifestations are dry mouth and eyes, which fall under the category of dryness impediment in Traditional Chinese Medicine (TCM). Currently, its etiology r2emains unclear. Western medical treatment primarily uses hormones and immunosuppressants, which often cause numerous adverse effects, and the disease is prone to recurrence and difficult to cure. This study primarily introduces the understanding and treatment of Sj?grens syndrome based on the One Qi Circuitism theory. Simultaneously, combined with visceral syndrome differentiation, it proposes the use of therapeutic methods such as fortifying the spleen, coursing the liver, and supplementing the kidney to regulate the balance of qi and yin, providing a theoretical basis for the TCM diagnosis and treatment of Sj?grens syndrome.

  Key words: : Sj?grens syndrome; Spleen; One Qi Circuitism; Pathogenesis; Therapeutic principle; HUANG Yuanyu

  Submit time: 7 January 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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