通讯作者: 王昌雄, wangchenbo2006@163.com

DOI：10.12201/bmr.202510.00024

The clinical efficacy of intestinal metal stent placement combined with She ethnic__________________

• 摘要：目的 探讨肠道金属支架置入术联合畲药验方承气汤(以下简称承气汤)对恶性肠梗阻(Malignant Bowel Obstruction,MBO)患者的临床治疗效果。方法 本研究纳入2021年4月至2024年12月期间于丽水市中医院收治的62例MBO住院患者。采用随机分组法,将患者均分为研究组(n=31)与对照组(n=31)。对照组患者仅接受肠道金属支架置入术加常规治疗。研究组患者在完成支架置入术后24小时,始服承气汤煎剂联合治疗。结果 临床症状改善情况：治疗第3天及第7天,研究组在腹胀腹痛、恶心呕吐、排气排便等核心临床症状的改善程度评分方面,均优于对照组(P<0.05)。症状缓解时间：研究组患者腹胀腹痛、恶心呕吐缓解时间以及肛门排气排便恢复时间均较对照组缩短(P<0.05)。功能状态与生活质量：研究组患者卡氏功能状态评分(Karnofsky Performance Status,KPS)及生活质量评分(Quality of Life,QOL)均高于对照组(P<0.05)。总体疗效：研究组临床总有效率达到96.8%,高于对照组87.1%(P<0.05)。住院时间：在需要姑息治疗或后续接受结肠根治性手术的患者亚组中,研究组的平均住院时间均短于对照组(P<0.05)。安全性：研究期间,两组患者均未发现肠道穿孔、出血或支架移位等相关并发症。结论 肠道金属支架置入术联合畲药验方承气汤治疗MBO,能有效、迅速地缓解患者临床症状,提升其功能状态和生活质量,缩短住院时间,且安全性良好。该综合治疗方案为MBO的临床管理提供了新的思路和有效方法。

  关键词： 恶性肠梗阻; 肠道金属支架; 畲药验方承气汤; 临床疗效; 中西医结合

   

  Abstract: ：Objective To evaluate the clinical efficacy of intestinal metal stent placement combined with the She-ethnic empirical formula Chengqi Decoction (hereinafter referred to as Chengqi Decoction) in patients with malignant bowel obstruction (MBO). Methods Sixty-two in-patients with MBO admitted to Lishui Hospital of Traditional Chinese Medicine between April 2021 and December 2024 were recruited.They were randomly assigned to a study group (n=31) and a control group (n=31).The control group received intestinal metal stent placement plus standard care, whereas the study group additionally started oral administration of Chengqi Decoction 24 h after stent deployment. Results Symptom improvement: On treatment days 3 and 7, the study group showed significantly better improvement scores than the control group for core symptoms such as abdominal distension/pain, nausea/vomiting, and passage of flatus/stool (P<0.05). Symptom-relief time: The time to relief of abdominal distension/pain and nausea/vomiting, as well as the time to recovery of anal flatus/stool passage, were all shorter in the study group (P<0.05). Functional status and quality of life: Karnofsky Performance Status (KPS) and Quality of Life (QOL) scores were significantly higher in the study group (P<0.05). Overall efficacy: The total clinical effective rate was 96.8 % in the study group versus 87.1 % in the control group (P<0.05). Length of stay: In subgroups requiring either palliative care or subsequent radical colectomy, the mean hospital stay was markedly shorter for the study group (P<0.05). Safety: No stent-related complications—such as intestinal perforation,bleeding,or stent migration—were observed in either group during the study period. Conclusion Combining intestinal metal stent placement with the She-ethnic Chengqi Decoction effectively and rapidly alleviates clinical symptoms, improves functional status and quality of life, and shortens hospitalization without compromising safety. This integrated regimen offers a novel and practical approach to the management of MBO.

  Key words: Smalignant bowel obstruction; intestinal metal stent; She-ethnic empirical formula Chengqi Decoction; clinical efficacy; integrated traditional Chinese and Western medicine.

  提交时间：2025-10-14

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• 序号	提交日期	编号	操作
  1	2025-09-18	bmr.202510.00024V1	下载

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