通讯作者: 徐克菲, 825913966@qq.com

DOI：10.12201/bmr.202409.00041

A case of treating lupus nephritis in a child with Belizumab combined with traditional Chinese medicine syndrome differentiation formula

• 摘要：目的：分析1例狼疮性肾炎患儿的诊治经过，探讨生物制剂联合中药辨证方治疗狼疮性肾炎的临床疗效及安全性。方法：报道1例以“肉眼血尿”就诊的狼疮性肾炎患儿的临床表现、实验室检查以及诊治经过，通过对治疗前后临床证候的改善、基础用药的调整以及血清补体、尿检等指标进行总结分析，讨论贝利尤单抗联合中药辨证方在治疗儿童狼疮性肾炎的临床疗效、安全性以及优势所在。结果：贝利尤单抗联合中药辨证方治疗，可快速控制狼疮性患儿的临床证候，血尿、蛋白尿水平以及疾病活动度，减少疾病复发。结论：对于难治性狼疮性肾炎，可采用贝利尤单抗联合中药辨证方治疗，以控制病情，减少疾病复发。

  关键词： 狼疮性肾炎; 肉眼血尿; 中西医结合

   

  Abstract: Objective: To analyze the diagnosis and treatment process of a child with lupus nephritis, and explore the clinical efficacy and safety of biological preparations combined with traditional Chinese medicine syndrome differentiation formulas in the treatment of lupus nephritis. Method: Report on the clinical manifestations, laboratory tests, and diagnosis and treatment process of a child with lupus nephritis who presented with gross hematuria. Through summarizing and analyzing the improvement of clinical symptoms before and after treatment, adjustment of basic medication, serum complement, urine tests, and other indicators, discuss the clinical efficacy, safety, and advantages of belimumab combined with traditional Chinese medicine syndrome differentiation formula in the treatment of pediatric lupus nephritis.Result: The combination of belimumab and traditional Chinese medicine syndrome differentiation formula can quickly control the clinical symptoms, hematuria, proteinuria levels, and disease activity of children with lupus, and reduce disease recurrence. Conclusion: For refractory lupus nephritis, the combination of belimumab and traditional Chinese medicine syndrome differentiation formula can be used to control the condition and reduce disease recurrence.

  Key words: Lupus nephritis; Visual hematuria; Integrated Traditional Chinese and Western Medicine

  提交时间：2024-09-21

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 陈豪特, 沈建武, 包烨华, 朱栎巧, 诸靖宇. 中西医结合治疗住院老年患者失眠症. 2024. doi: 10.12201/bmr.202407.00059

  王可欣, 张少强. 不同功效组合的中药复方联合常规西药治疗冠心病合并抑郁的网状Meta 分析. 2024. doi: 10.12201/bmr.202410.00055

  周海, 彭斐灵, 韦昌法. 中医诊断学辨证知识图谱构建研究与实践. 2020. doi: 10.12201/bmr.202004.00036

  白晶雪, 雷根平, 王婷, 董盛, 谢炯东, 陆娴, 杨东. 中药复方治疗特发性膜性肾病的安全性及有效性网状Meta分析. 2024. doi: 10.12201/bmr.202412.00003

  王先菊, 司建平, 郭清. 居家社区中医药特色医养结合服务绩效评价指标体系构建研究. 2023. doi: 10.12201/bmr.202312.00004

  张馨瑞, 凌平, 叶露, 刘勇攀, 倪思忆, 沈雁. 基于中医动态思维探讨湿热在溃疡性结肠炎中的中西医病机特点. 2024. doi: 10.12201/bmr.202409.00040

  付涛涛, 陈艳梅, 李庆娜, 邵义明, 苏国彬, 弓孟春. 基于《中国药典》的中药知识图谱的构建与应用. 2024. doi: 10.12201/bmr.202407.00039

  陈书逸, 何飞. “保胃气”在辨治非结核分枝杆菌肺病的应用. 2024. doi: 10.12201/bmr.202407.00002

  刘金梅, 周太, 郑青. 试论“文化传承”视域下中医药文化的连续性. 2024. doi: 10.12201/bmr.202412.00013

  朱欣叶, 钱爱兵. 我国中医药人力资源的空间特征及动态演进. 2023. doi: 10.12201/bmr.202312.00009

• 序号	提交日期	编号	操作
  1	2024-05-23	bmr.202409.00041V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论