戚天凤, 王婉婷, 韦乐, 高秀飞. 从“龙火离位”探析引火归元法治疗乳腺癌内分泌治疗相关潮热. 2026. biomedRxiv.202604.00117
从“龙火离位”探析引火归元法治疗乳腺癌内分泌治疗相关潮热
通讯作者: 高秀飞, gaoxiufei@zcmu.edu.cn
DOI:10.12201/bmr.202604.00117
Exploring the “Guiding Fire Back to Its Origin” Method for Endocrine Therapy–Related Hot Flashes in Breast Cancer from the Perspective of “Displacement of Dragon Fire”
Corresponding author: GAO Xiufei, gaoxiufei@zcmu.edu.cn
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摘要:乳腺癌术后内分泌治疗常引发潮热,严重影响患者生活质量与治疗依从性。该症状的中医病机较为复杂,“龙火离位”是阐释部分患者核心病机的重要理论之一,主要分为“水浅不养龙,阴虚致阳浮”与“水寒不藏龙,下寒致上热”两类证型。引火归元法作为中医从治之法,通过滋阴潜阳或温补肾阳,使离位之相火重归肾元,与符合此特定病机的潮热证候高度契合。然此法仅为针对特定证型的治法之一,非本病之通用总则。文章基于中医理论,初步探析引火归元法在乳腺癌内分泌治疗相关潮热中的理论依据与应用价值,以期为临床提供新思路。
Abstract: Endocrine therapy after breast cancer surgery frequently induces hot flashes, which significantly impair patients’ quality of life and adherence to treatment. In traditional Chinese medicine (TCM), the core pathogenesis of this condition is summarized as the “displacement of dragon fire,” with two major syndromic patterns: “insufficient water failing to nourish the dragon, leading to yin deficiency and floating yang”; and “cold water failing to store the dragon, resulting in lower cold and upper heat”. The therapeutic principle of Guiding Fire Back to Its Origin (Yin Huo Gui Yuan), a representative reverse-regulation strategy in TCM, restores displaced ministerial fire to the kidney origin through nourishing yin to subdue yang or warming and tonifying kidney yang. This mechanism shows high consistency with the pathogenesis of hot flashes induced by endocrine therapy. Based on TCM theory, this paper preliminarily explores the theoretical foundation and potential clinical value of this method in managing endocrine therapy–related hot flashes in breast cancer, aiming to provide new insights for treatment.
Key words: guiding fire back to its origin; hot flashes; breast cancer; endocrine therapy提交时间:2026-04-14
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序号 提交日期 编号 操作 1 2026-04-02 10.12201/bmr.202604.00117V1
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