通讯作者: 彭智平, pengzhiping136826@126.com

DOI：10.12201/bmr.202603.00085

Exploring the Effect of Laifu Decoction on Chronic Heart Failure of yuan qi deficiency Based on the

• 摘要：目的 在“肝主脱”理论指导下探讨来复汤治疗元气亏虚型慢性心力衰竭的效果。方法 选取2024年2月至2025年10月本院收治的64例元气亏虚型CHF患者,随机分为对照组32例和中药组32例。对照组采用常规治疗,中药组在对照组基础上加用来复汤治疗。比较两组疗效、中医证候积分、心功能及糖脂代谢水平。结果 中药组、对照组总有效率分别为87.50%(21/32)、65.63%(28/32),中药组高于对照组(P<0.05)。两组治疗后中医证候积分较治疗前均下降,且中药组下降更多(P<0.05)。与治疗前相比,中药组治疗后B型利钠肽水平下降(P<0.05)。两组治疗前、后肌钙蛋白I水平比较无差异(P>0.05)。对照组治疗后胰岛素水平、胰岛素抵抗指数较治疗前下降(P<0.05),而两组治疗前及治疗后INS、HOMA-IR、葡萄糖、游离脂肪酸水平比较均无差异(P>0.05)。结论 基于“肝主脱”理论来复汤治疗元气亏虚型CHF患者能降低其中医证候积分、改善心功能,且临床疗效较好。

  关键词： 来复汤; 元气亏虚证; 慢性心力衰竭; 应用效果

   

  Abstract: Objective To investigate the application effect of Laifu decoction on chronic heart failure (CHF) with yuan qi deficiency based on the Liver Governs Collapse. Methods From Feb, 2024 to Oct, 2025, 64 patients with CHF of yuan qi deficiency in our hospital were randomly divided into control group (32 cases) and traditional Chinese medicine group (32 cases). The control group was treated with conventional western medicine, the traditional Chinese medicine group was administered Laifu decoction on top of the control group. The therapeutic effect, TCM syndrome score, cardiac function and glucose and lipid metabolism levels were compared between the two groups. Results The total effective rates of the traditional Chinese medicine group and the control group were 87.50% (21/32) and 65.63% (28/32) respectively, and the traditional Chinese medicine group was higher than that of the control group (P<0.05). After treatment, the TCM syndrome scores of both groups decreased compared with those before treatment, and the decrease was greater in the TCM group (P<0.05). Compared with before treatment, the level of B-type natriuretic peptide in the traditional Chinese medicine group decreased after treatment (P<0.05), There was no difference in the levels of troponin I between the two groups before and after treatment(P>0.05). Compared to their baseline, the control group showed a significant reduction in insulin (INS) and insulin resistance index (HOMA-IR) levels post-treatment (P<0.05). In contrast, the levels of INS, HOMA-IR, glucose, and free fatty acids showed no significant intergroup differences at either time point between the two groups(P>0.05). Conclusion Based on the Liver Governing Dispersing theory, Laifu decoction in the treatment of CHF patients with deficiency of yuan qi could reduce the TCM syndrome score, improve heart function, and had a good clinical effect.

  Key words: Laifu decoction; Yuan qi deficiency; Chronic heart failure; Application effect

  提交时间：2026-03-19

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• 序号	提交日期	编号	操作
  1	2026-03-08	10.12201/bmr.202603.00085V1	下载

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