• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

[title missed]

Corresponding author: yangyexiang, yyxzzy@163.com
DOI: 10.12201/bmr.202507.00043
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Abstract Objective: To explore the intervention effect of grading activities on postoperative delirium in patients undergoing total hip arthroplasty. Method: 100 patients aged ≥ 50 years who underwent total hip arthroplasty in the Third Affiliated Hospital of Sun Yat-sen University from January 2024 to January 2025 were selected as the study subjects. They were randomly divided into an experimental group and a control group, with 50 patients in each group, using a random number table method. The control group received routine postoperative care, while the experimental group began intervention according to the early grading activity plan upon returning to the ward after surgery. Compare the incidence of delirium, Harris Hip Joint Function Scale, Pittsburgh Sleep Quality Index score, average length of hospital stays, average hospital expenses, and satisfaction between two groups of patients. Result: The incidence of postoperative delirium was significantly lower in the experimental group than in the control group (4% vs. 18%, P < 0.05). The results of the Harris Hip Function Score (HHFS) total score and sub-scores showed that the experimental group had a significantly higher total score (80.94 ± 7.53 vs. 76.54 ± 5.95), pain score (37.36 ± 5.22 vs. 34.96 ± 5.22) and joint function score ( 38.64 ± 3.84 vs. 36.96 ± 3.79) were significantly higher than those of the control group (P < 0.05), but there was no statistically significant difference between the two groups in terms of deformity and mobility (P > 0.05). In addition, the incidence rate of difficulty in sleeping (10.0% vs. 28.0%), the mean number of days of hospitalisation (11.86 ± 2.61 d vs. 13.42 ± 2.95 d), the cost of hospitalisation (33,581.16 ± 6,257.20 yuan vs. 38,438.72 ± 7,816.95 yuan), and the satisfaction rate (94.0% vs. 78.0%) in the experimental group were all were significantly better than those of the control group (P < 0.05). Conclusion: Early grading activities can prevent postoperative delirium in patients undergoing total hip arthroplasty, alleviate postoperative pain, improve joint function and sleep quality, reduce average length of hospital stay and hospitalization costs, and increase patient satisfaction.

    Key words: Total Hip Arthroplasty; Postoperative Delirium; Grading activities; Joint pain; Joint function

    Submit time: 14 July 2025

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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    1 2025-06-09

    bmr.202507.00043V1

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yangyexiang, wangkun, liangtangzhao, guandandan. [title missed]. 2025. biomedRxiv.202507.00043

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