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Corresponding author: guying, 1137865395@qq.com

DOI: 10.12201/bmr.202506.00040

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  Abstract: Polymyalgia Rheumatica (PMR) is a common rheumatic disease in the elderly population. To outline its current diagnostic and therapeutic landscape, this article reviews recent domestic and international studies, summarizing the pathogenesis and therapeutic advances in both Traditional Chinese Medicine (TCM) and Western medicine. The results indicate that Western medicine has made significant progress in exploring immune dysregulation and genetic associations, yet treatment remains centered on glucocorticoids, with unresolved challenges such as long-term medication side effects and recurrence. Based on TCM theory, staged classification and external therapies may synergize with glucocorticoids to enhance efficacy and reduce toxicity. However, limited research on specific active components and molecular mechanisms hinders international recognition of TCM therapies. Integrated Traditional Chinese and Western Medicine shows potential in reducing glucocorticoid dependence and relapse rates. Future efforts should focus on developing biomarkers, establishing standardized diagnostic and therapeutic protocols, and conducting high-quality clinical trials to optimize treatment strategies.

  Key words: Polymyalgia Rheumatica; Integrated Traditional Chinese and Western Medicine; Treatment; Research Advances; Review

  Submit time: 18 June 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2025-06-03	bmr.202506.00040V1	Download

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