通讯作者: 古英▲, 1137865395@qq.com

DOI：10.12201/bmr.202506.00040

• 摘要：风湿性多肌痛(PMR)是老年人群常见的风湿性疾病。为梳理其诊疗现状,本文通过综述近年国内外研究,总结其中西医发病机制及治疗进展。结果显示,西医在免疫异常及遗传关联研究方面较为深入,但治疗仍以糖皮质激素为核心,长期用药副作用及复发问题仍待解决。基于中医基础理论,通过分期分型及外治法可协同激素增效减毒,但具体活性成分及分子机制研究匮乏,制约中医疗法在国际上的认可。中西医结合在减少激素依赖、降低复发率方面展现潜力。未来需聚焦生物标志物开发、诊疗规范建立及高质量临床验证,以推动治疗策略优化。

  关键词： 风湿性多肌肉痛; 中西医结合; 治疗; 研究进展; 综述

   

  Abstract: Polymyalgia Rheumatica (PMR) is a common rheumatic disease in the elderly population. To outline its current diagnostic and therapeutic landscape, this article reviews recent domestic and international studies, summarizing the pathogenesis and therapeutic advances in both Traditional Chinese Medicine (TCM) and Western medicine. The results indicate that Western medicine has made significant progress in exploring immune dysregulation and genetic associations, yet treatment remains centered on glucocorticoids, with unresolved challenges such as long-term medication side effects and recurrence. Based on TCM theory, staged classification and external therapies may synergize with glucocorticoids to enhance efficacy and reduce toxicity. However, limited research on specific active components and molecular mechanisms hinders international recognition of TCM therapies. Integrated Traditional Chinese and Western Medicine shows potential in reducing glucocorticoid dependence and relapse rates. Future efforts should focus on developing biomarkers, establishing standardized diagnostic and therapeutic protocols, and conducting high-quality clinical trials to optimize treatment strategies.

  Key words: Polymyalgia Rheumatica; Integrated Traditional Chinese and Western Medicine; Treatment; Research Advances; Review

  提交时间：2025-06-18

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2025-06-03	bmr.202506.00040V1	下载

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