Analysis of medication rules of plaster method in

Corresponding author: FAN Xiao-liang, fanxiaoliang1022@163.com

DOI: 10.12201/bmr.202504.00072

•  

  Abstract: Objective: To analyze the medication rules of plaster prescriptions in Li Yue Pian Wen based on the traditional Chinese medicine inheritance assistance platform software (V3.5)，and provide a reference for the clinical use of plaster prescriptions to treat diseases. Methods: Collect the plaster prescriptions used in Li Yue Pian Wen, including the scattered drugs and application drugs used in conjunction with plasters for systematic analysis. Enter the data into the software and use the integrated data mining method.. Through the prescription analysis module, analyze the four qi and five flavors, nature and meridian tropism, medication frequency, and prescription combination rules of prescriptions. After analyzing the core drug combinations through complex system entropy clustering, new prescriptions are evolved. In addition, analyze the application rules of scattered drugs in scattered drug prescriptions separately, and analyze the plaster-condensing drugs and drugs involved in the eighteen incompatible and nineteen mutual restraint pairs in plaster prescriptions. Results: Among 290 plaster prescriptions and prescriptions for scattered drugs and application drugs, it was found that the four qi of drug properties were mainly warm and cold, the five flavors were mainly pungent, bitter, and sweet, and the meridian tropisms covered all meridians. Through cluster analysis, 29 core combinations and 6 new prescriptions are evolved. The top three drugs in scattered drug prescriptions are CortexCinnamomi, CoptidisRhizoma, and Caryophylli Flos. Among 158 plaster prescriptions, 153 were black plasters, and a total of 76 prescriptions involved the use of drug pairs in the eighteen incompatible and nineteen mutual restraint pairs. Conclusion: It was found that the medication combinations in Li Yue Pian Wen had diversity and concentration in medication, and contained the concept that internal and external treatments lead to the same goal. It can provided some new diagnostic and treatment ideas for the clinical application of external treatment plasters.

  Key words: Li Yue Pian Wen; plasters; medication rules; data mining

  Submit time: 27 April 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• Wei Chunshan. Exploring medication rules and mechanism for liver cancer based on data mining and network pharmacology. 2024. doi: 10.12201/bmr.202407.00040

  HU Xinxin, GAO Chuchu, ZHU Xueme, PAN Yiyi. Analysis of Medication Patterns for Treating Menstrual Disorders with Chong and Ren Disharmony Based on Real-World Data Mining. 2024. doi: 10.12201/bmr.202412.00026

  ZHENG Yongfei, ZHOU Minhua, YE Yiping. Study on the regularity of medication of Director Ye Yiping in the treatment of lung cancer based on data mining methods. 2024. doi: 10.12201/bmr.202407.00030

  Based on data mining, the medication rule of Professor Zhong Jie in the treatment of ovarian reserve dysfunction was discussed. 2025. doi: 10.12201/bmr.202504.00005

  limengfan, zhangllin, zhangyiwei. Exploration of the Medication Patterns and Mechanisms in the Treatment of Insomnia by Professor Liang Hui Based on Data Mining Analysis. 2024. doi: 10.12201/bmr.202410.00039

  WANG Xiaoyan, LIU Liping, KOANG Lingxia, ZHENG Xiaojuan, CHUN Zhuo. Exploring the Medication Patterns of Pediatric Night Cough Treatment Based on the Shaoyang Pivot Theory through Data Mining. 2025. doi: 10.12201/bmr.202502.00014

  Ma Wei-Rong, Chen Jie, Yang Yin-Qian, Tan Yong. Study on the rules of medication in treating female Infertility in Jiyin Gangmu·Qiuzimen. 2024. doi: 10.12201/bmr.202411.00067

  LiYu, Yang Tao, Hu Kongfa. Research on Medication Rules of Famous TCM Physicians in Treating Lung Cancer Based on Hierarchical Community Partition Algorithm. 2021. doi: 10.12201/bmr.202110.00020

  刘永珍, Wang ling, Liu Fu Ron. Medication patterns of traditional Chinese medicine in the treatment of radiotherapy-induced oral mucositis:A study based on data mining. 2025. doi: 10.12201/bmr.202504.00049

  Yang enfa, Wen Lingzhi, Huang Jianping. An Examination of Ye Tianshis Therapeutic Approaches to Internal Wind Utilizing Data Mining Techniques.. 2024. doi: 10.12201/bmr.202412.00020

• ID	Submit time	Number	Download
  1	2025-04-09	bmr.202504.00072V1	Download

• Public  Anonymous  To author only Submit Comments