• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

The predictive value ofperipheral blood inflammatory makers for lower extremity deep venous thrombosis after hip fracture surgery in patients

DOI: 10.12201/bmr.202408.00016
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: 【Abstract】 Objectives To investigate the value of peripheral blood inflammatory makers after hip fracture surgery in patients. Methods Patients with hip fracture who underwent surgery from August 2022 to July 2023 were selected and divided into DVT group and non-DVT group according to whether DVT occurred. The general data and laboratory indicators of the two groups were statistically analyzed, and the predictive value of peripheral blood inflammatory makers on postoperative DVT in patients with hip fracture was evaluated by ROC curve. Results 485 samples were included, including 61 cases in the DVT group and 424 cases in the non-DVT group, and the incidence of DVT was 12.58%. The levels of SII, NLR and D-dimern in DVT group were higher than those in non-DVT group,and the LMR in DVT group was lower than that in non-DVT group, the difference was statistically significant (P<0.05). Multivariate analysis showed that NLR, combined cardiovascular disease, bed time before operation and surgical method were independent risk factors for postoperative DVT in patients with hip fracture. ROC showed that AUC of NLR was 0.606, and the combined AUC of NLR+ D-dimer was 0.628 Conclusions Combining the levels of NLR and D-dimer in patients with hip fractures, as well as their preoperative bed rest time and comorbidities, has certain predictive value for the occurrence of postoperative DVT

    Key words: Peripheral blood inflammatory makers;Hip fracture; Thrombus

    Submit time: 9 August 2024

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  • ID Submit time Number Download
    1 2024-06-19

    bmr.202408.00016V1

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[authors missed]. The predictive value ofperipheral blood inflammatory makers for lower extremity deep venous thrombosis after hip fracture surgery in patients. 2024. biomedRxiv.202408.00016

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