Development of the conceptual framework for health-related quality of life in Chinese populations: A qualitative study based on the general population and patients

Corresponding author: WU Jing, jingwu@tju.edu.cn

DOI: 10.12201/bmr.202407.00012

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  Abstract: Objective: To explore the understanding on health-related quality of life (HRQoL) among the Chinese populations and to develop a HRQoL conceptual framework that can be used to guide the development of Chinese HRQoL instruments. Methods: Respondents of Chinese general population and patients populations were recruited from 31 provinces in China. One-to-one semi-structured qualitative interviews were conducted to collect the views and perceptions on HRQoL. Based on the grounded theory, multi-level coding of qualitative interviews was carried out, and the framework method was used to sort out and summarize the coding to develop the HRQoL conceptual framework in China. Results: A total of 68 respondents, including 40 general population and 28 disease patients, were included in the study. The study extracted 1,558 open coding from the qualitative interview, which were analyzed and sorted into 180 axial coding and 31 selective coding (dimensions). The HRQoL conceptual framework for the Chinese population with 6 themes was finally summarized. Conclusion: The HRQoL conceptual framework based on the health concepts and preferences of the Chinese population contains 6 themes, refers to symptoms, physical function, emotion, cognition, activities and social function. In particular, the items of appetite, sleep and fatigue identifies may reflect Chinese cultural specific perceptions on important aspects of HRQoL.

  Key words: Health-related quality of life, Conceptual framework, Chinese population, Qualitative study

  Submit time: 10 July 2024

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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