Impact of Enhanced Recovery After Surgery Protocols on Outcomes Following Percutaneous Vertebroplasty in Elderly Patients with Osteoporotic Vertebral Compression Fractures

Corresponding author: Tuerhong Tuerxun, 18309919537@163.com

DOI: 10.12201/bmr.202604.00105

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  Abstract: Abstract: Objective: Exploring the clinical application value of the Enhanced Recovery Surgery (ERAS) concept in percutaneous vertebroplasty (PVP) for the treatment of osteoporotic vertebral compression fractures (OVCF). Methods：This trial was conducted between June 2024 and June 2025, enrolling 62 patients with OVCF undergoing PVP. Patients were allocated via a randomised number combined interval block design to either the ERAS intervention group (n=31) or the standard care control group (n=31).The ERAS group received standardised interventions covering preoperative, intraoperative, and postoperative phases. Visual analogue scale (VAS) scores, Oswestry Disability Index (ODI) scores, and Barthel Index (BI) scores were compared between groups at admission, 2 days postoperatively, and at 1 and 3 months postoperatively. Additional perioperative assessment parameters included mean operative duration, total hospital stay, postoperative hospitalisation duration, inpatient costs, complication incidence, and patient satisfaction with hospitalisation. Results: The ERAS group demonstrated superior VAS scores at 2 days post-surgery (p<0.001) and 1 month post-surgery (p=0.008), as well as superior BI scores (p<0.001) and ODI scores (p<0.001) at both 2 days and 1 month post-surgery compared to the control group. No significant differences were observed between groups in VAS, BI, or ODI scores at 3 months postoperatively. The mean postoperative hospital stay was comparable between groups, though the ERAS group exhibited a shorter total hospital duration (p=0.006). Furthermore, while mean operative times were equivalent, the ERAS group demonstrated higher patient satisfaction (p=0.025) and a lower overall complication rate (p=0.031).Conclusion: The application of ERAS to PVP treatment for OVCF is safe and effective, significantly alleviating early postoperative pain, shortening hospital stays, promoting functional recovery, reducing complications, and enhancing patient satisfaction.

  Key words: Enhanced Recovery After Surgery; Osteoporosis; Compression Fracture; PVP

  Submit time: 13 April 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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