李文财, 严梦杰, 周圆, 吐尔洪·吐尔逊. 加速康复外科在老年骨质疏松性椎体压缩性骨折经皮椎体成形术中的应用. 2026. biomedRxiv.202604.00105
加速康复外科在老年骨质疏松性椎体压缩性骨折经皮椎体成形术中的应用
通讯作者: 吐尔洪·吐尔逊, 18309919537@163.com
DOI:10.12201/bmr.202604.00105
Impact of Enhanced Recovery After Surgery Protocols on Outcomes Following Percutaneous Vertebroplasty in Elderly Patients with Osteoporotic Vertebral Compression Fractures
Corresponding author: Tuerhong Tuerxun, 18309919537@163.com
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摘要:摘 要:目的 :探究加速康复外科(Enhanced Recovery After Surgery, ERAS)理念在经皮椎体成形术(Percutaneous Vertebroplasty, PVP)治疗骨质疏松性椎体压缩性骨折(Osteoporotic Vertebral Compression Fracture, OVCF)中的临床应用价值。方法 这项研究于2024年6月至2025年6月进行,纳入62例接受PVP的OVCF患者,将患者通过随机数字联合区间区组设计分为ERAS试验组(n=31)与常规护理对照组(n=31)。ERAS组在术前、术中、术后等方面进行规范化干预。比较两组入院时、术后2天、1个月和3个月时的视觉模拟量表评分(visual analogue scale,VAS)、Oswestry功能障碍指数(Oswestry Disability Index,ODI)评分和Barthel指数(Barthel Index,BI)评分。围术期其他评估参数包括平均手术时长、总住院时间、术后住院时间、住院成本、并发症发生率及患者住院满意度。结果:ERAS组在术后2天(P<0.001)和术后 1 个月(P=0.008)的VAS评分、术后 2 天和 1 个月的 BI 评分(P<0.001)及ODI评分(P<0.001)均优于对照组。两组术后3个月的VAS评分、BI评分和ODI评分无明显差异。两组在术后平均住院时间无显著差异,但ERAS组的总住院时间更短(P=0.006)。此外,两组平均手术时长相当,但ERAS组患者满意度更高(P=0.025),并发症总体发生率更低(P=0.031)。结论:将ERAS应用于PVP治疗OVCF是安全有效的,可显著缓解术后早期疼痛、缩短住院时间、促进功能恢复、减少并发症并提高患者满意度。
Abstract: Abstract: Objective: Exploring the clinical application value of the Enhanced Recovery Surgery (ERAS) concept in percutaneous vertebroplasty (PVP) for the treatment of osteoporotic vertebral compression fractures (OVCF). Methods:This trial was conducted between June 2024 and June 2025, enrolling 62 patients with OVCF undergoing PVP. Patients were allocated via a randomised number combined interval block design to either the ERAS intervention group (n=31) or the standard care control group (n=31).The ERAS group received standardised interventions covering preoperative, intraoperative, and postoperative phases. Visual analogue scale (VAS) scores, Oswestry Disability Index (ODI) scores, and Barthel Index (BI) scores were compared between groups at admission, 2 days postoperatively, and at 1 and 3 months postoperatively. Additional perioperative assessment parameters included mean operative duration, total hospital stay, postoperative hospitalisation duration, inpatient costs, complication incidence, and patient satisfaction with hospitalisation. Results: The ERAS group demonstrated superior VAS scores at 2 days post-surgery (p<0.001) and 1 month post-surgery (p=0.008), as well as superior BI scores (p<0.001) and ODI scores (p<0.001) at both 2 days and 1 month post-surgery compared to the control group. No significant differences were observed between groups in VAS, BI, or ODI scores at 3 months postoperatively. The mean postoperative hospital stay was comparable between groups, though the ERAS group exhibited a shorter total hospital duration (p=0.006). Furthermore, while mean operative times were equivalent, the ERAS group demonstrated higher patient satisfaction (p=0.025) and a lower overall complication rate (p=0.031).Conclusion: The application of ERAS to PVP treatment for OVCF is safe and effective, significantly alleviating early postoperative pain, shortening hospital stays, promoting functional recovery, reducing complications, and enhancing patient satisfaction.
Key words: Enhanced Recovery After Surgery; Osteoporosis; Compression Fracture; PVP提交时间:2026-04-13
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序号 提交日期 编号 操作 1 2026-01-13 10.12201/bmr.202604.00105V1
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