The Clinical Effect Of The Auricular Tip Bloodletting Combined With Chaige Jieji Decoction In Treating Acute Viral Infection Fever of the Upper Respiratory Tract

Corresponding author: Zeng YunPing, zyp810920@163.com

DOI: 10.12201/bmr.202602.00089

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  Abstract: Objective To observe the clinical efficacy of auricular apex bloodletting therapy combined with Chaige Jieji Decoction in patients with fever caused by acute upper respiratory viral infection. Methods A total of 90 patients with fever due to acute upper respiratory viral infection, admitted to the Department of Respiratory Medicine and Fever Clinic from January 2024 to January 2025, were enrolled. They were randomly divided into three groups (30 cases each) using a random number table: the Western medicine group, Chinese medicine group, and combined acupuncture-medicine group. The Western medicine group received conventional antipyretic treatment with paracetamol tablets. The Chinese medicine group was treated with oral decocted Chaige Jieji Decoction. The combined group received auricular apex bloodletting therapy in addition to the Chinese medicine treatment. The onset time of antipyretic effect, time to complete defervescence, Traditional Chinese Medicine (TCM) symptom scores (fever, chills, cough, sore throat, headache and body pain), clinical efficacy, and adverse events were compared before and after treatment. Results Compared with the other two groups, the acupuncture-medication combination group demonstrated a higher overall response rate, as well as shorter time to onset of antipyresis and time to complete fever resolution (P<0.05). After treatment, the TCM symptom scores were all reduced in the three groups(P<0.05). The reduction was more pronounced in the acupuncture-medication combination group than in the other two groups (P<0.05). No treatment-related adverse events occurred in any of the groups. Conclusion Auricular apex bloodletting therapy combined with Chaige Jieji Decoction is effective in treating fever due to acute upper respiratory viral infection. It can rapidly exert antipyretic pathway-related effects, inhibit the production and activation of inflammatory cytokines, regulate the immune system, and has both efficacy advantages and safety.

  Key words: Acute viral upper respiratory tract infection; Fever; The Auricular Tip Bloodletting; Chaige Jieji Decoction; Acupuncture-Pharmacotherapy Integration

  Submit time: 23 February 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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