通讯作者: 袁岳鹏, 2048892060@qq.com

DOI：10.12201/bmr.202507.00080

Exploration of the pathogenesis of vascular depression based on the theory of heart-brain homoeopathy in the treatment of vascular depressionLU Caiju1,HE Xin1,YUAN Yuepeng2,MA Tiantian1,ZHU Yuanheng1,XU Yiguo2,WANG Weilong2

• 摘要：血管性抑郁症(Vascular Depression,VD)是指由脑血管病变(如缺血性损伤?白质病变或微循环障碍等)引起的睡眠障碍?兴趣减退?情绪低落?记忆力下降等1为核心临床症状的精神疾病2,现代医学认为,其发病机制与脑血管病变导致前额叶-边缘系统神经环路功能紊乱密切相关?中医认为血管性抑郁与心、脑关系密切,心主神明,而心脑相通,神志共主,心气上通于脑,又心主血脉,濡养脑神,脑为心神之器,为心神活动的物质基础,二者通过经络相连构成“心脑相通”的整体系统?若因年老五脏虚衰以致心气不足?肾精亏损与气血运行不畅以致心脉瘀阻脑络导致心失所养而神机不运,脑髓失充而神明失用,最终表现为情绪抑郁?思维迟缓?夜寐不安等神志异常症状?本文基于“心脑同治”理论,从“心主血以养脑”?“脑为神机以统心”的生理角度出发,系统探讨心脑功能失调在血管性抑郁症发病中的核心病机,为中医从心脑论治血管性抑郁症提供理论依据?

  关键词： 心脑同治,血管性抑郁症,理论探讨; 

   

  Abstract: Vascular Depression (VD) is a psychiatric disorder caused by cerebrovascular lesions (e.g., ischemic injury, white matter lesions, or microcirculatory disorders, etc.), with sleep disorders, loss of interest, depressed mood, and memory loss as the core clinical symptoms , and modern medical science suggests that its pathogenesis is closely related to the functional disorders of the prefrontal-limbic neural loop caused by cerebrovascular lesions. Modern medicine believes that its pathogenesis is closely related to the cerebrovascular lesions leading to prefrontal-limbic system neurological disorders. Chinese medicine believes that vascular depression is closely related to the heart and brain, recognizing that the heart is the master of God, and the heart and brain are connected, and God is the master of the heart and brain, and the heart is the master of the blood, and the brain and God are moistened and nourished, and the brain is the instrument of the heart and God, and the material basis of the heart and Gods activities. The two are connected through the meridians to form a whole system of “heart-brain connection”. If the deficiency of heart qi and loss of kidney essence due to the weakness of the five viscera in old age and the stagnation of heart veins and brain channels due to the poor operation of qi and blood in old age lead to the loss of nourishment of the heart and the lack of movement of the divine mechanism, the loss of the brain marrow and the loss of use of the divine, which will ultimately be manifested as depression, slow thinking, sleeplessness at night, and other abnormal symptoms of the spirit and mind. Based on the theory of heart-brain treatment, this article starts from the physiological interaction of heart masters the blood to nourish the brain and brain is the divine mechanism to unify the heart,and systematically explores the core mechanism of heart-brain dysfunction in the pathogenesis of vascular depression, so as to provide theoretical basis for the treatment of vascular depression in Chinese medicine from the theory of heart-brain.

  Key words: Cardio-cerebral homoeopathy,Vascular depression; Theoretical discussion

  提交时间：2025-07-31

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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  1	2025-07-07	bmr.202507.00080V1	下载

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