通讯作者: 秦祖杰, 109741754@qq.com

DOI：10.12201/bmr.202507.00063

Based on Data Mining:Analysis of Medication Rules and Clinical Experience for Asthenia

• 摘要：目的 利用Excel 2021、SPSS Modeler18.0、SPSS Statistics27.0.1探析秦祖杰教授治疗虚劳的用药规律及临床经验。 方法 收集2024年1月至2024年12月秦教授门诊诊断为虚劳的医案及处方构建数据库并进行规范化处理，并通过频数统计、关联规则分析、聚类分析等统计方法剖析其用药特点及诊疗经验。结果 获得门诊处方148首，涵盖中药171味，总频次2109次，频次＞30次的中药20味，前五味为炙甘草、白术、当归、黄芪、柴胡。药物属性统计结果示：药性以温、平、微寒为主，药味以甘、辛、苦为主，归经以脾经为主，功效以补虚药为主，其中补气药最为常见。关联规则分析得出最常用的前3组药对为白术-党参、白术-升麻、当归-升麻；聚类分析得到3首处方。 结论 秦教授治疗虚劳的用药规律总结为：一、抓气血，顾脾胃，疏调并举；二、养先天，补后天，顾根本；三、补虚为主，解毒为辅，标本兼顾。

  关键词： 虚劳 用药规律 数据挖掘 临床经验; ; ; 

   

  Abstract: Objective The medication patterns and clinical experience of Professor Qin Zujie in the treatment of deficiency labor were explored by using Excel 2021, SPSS Modeler 18.0 and SPSS Statistics27.0.1. Methods The medical cases and prescriptions of Professor Qins outpatient diagnosis of deficiency labor from January 2024 to December 2024 were collected to construct a database and undergo standardized processing. His medication characteristics and diagnosis and treatment experience were analyzed through statistical methods such as frequency statistics, association rule analysis, and cluster analysis. Results A total of 148 valid outpatient prescriptions were screened, involving 171 herbal medicines with a cumulative frequency of 2,109. Twenty Chinese and Zhuang medicines had frequencies >30, with the top five being Glycyrrhizae Radix Praeparata,Atractylodis Macrocephalae Rhizoma,Angelicae Sinensis Radix,Astragali Radix,and Bupleuri Radix. Statistical analysis of herb properties revealed that warm, neutral, and slightly cold natures were predominant; sweet, pungent, and bitter flavors were most common; the spleen meridian was the primary channel tropism; and tonifying herbs (especially qi-tonifying herbs) were the most frequently used. Association rule mining identified the top three herb pairs as Atractylodis Macrocephalae Rhizoma-Codonopsis Radix,Atractylodis Macrocephalae Rhizoma-Cimicifugae Rhizoma, and Angelicae Sinensis Radix-Cimicifugae Rhizoma. Cluster analysis yielded three core prescription patterns. Conclusion Professor Qin’s medication rules for consumptive disease can be summarized as: (1) Emphasizing qi and blood regulation while harmonizing the spleen and stomach; (2) Nourishing both innate and acquired constitutions to consolidate fundamental health; and (3) Prioritizing tonification while incorporating detoxification for holistic treatment.

  Key words: Asthenia; Medication Rules; Data Mining; Clinical Experience

  提交时间：2025-07-20

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• 序号	提交日期	编号	操作
  1	2025-06-17	bmr.202507.00063V1	下载

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