通讯作者: 郑学菊, 540976866@qq.com

DOI：10.12201/bmr.202506.00046

Effect of acupoint catgut embedding on Apelin and adiponectin in obese PCOS patients

• 摘要：目的：基于“重阳”理论，研究穴位埋线治疗肥胖型PCOS的临床效果。方法：将2023年1月—2023年12月贵州中医药大学第一附属医院60例肥胖型PCOS患者随机分为3组，对照组用二甲双胍治疗，治疗A组用穴位埋线联合二甲双胍治疗，治疗B组仅用穴位埋线治疗，对比3组治疗前后Apelin、ADP水平变化。结果：（1）治疗后三组的Apelin水平均低于治疗前（P＜0.05）；对照组的Apelin水平高于治疗A组和治疗B组的Apelin（P＜0.05），然而，治疗A组和治疗B组之间的差异在统计学上并不显著（P>0.05）；（2）经过治疗，三组患者的ADP水平都呈现出上升的趋势（P<0.05）（2）治疗后三组的ADP水平均有所上升（P＜0.05）；治疗A组和治疗B组的数值都明显高于对照组（P<0.05），但在治疗A组和治疗B组之间的差异并没有统计学上的显著性（P>0.05）；（3）经过治疗，三组患者的WHR和BMI水平都明显低于治疗前的水平（P<0.05）；治疗A组改善WHR、BMI水平明显优于治疗B组，治疗B组又优于对照组（P＜0.05）。结论?：基于“重阳”理论，通过穴位埋线治疗肥胖型PCOS，可以降低Apelin、WHR、BMI水平，升高ADP水平，从而改善多囊卵巢综合征脂代谢水平，为穴位埋线治疗肥胖型PCOS提供理论研究基础。

  关键词： 多囊卵巢综合征; 肥胖型; 穴位埋线; Apein; ADP

   

  Abstract: To study the clinical effect of acupoint catgut embedding in the treatment of obese PCOS based on the theory of Chongyang . Methods : From January 2023 to December 2023,60 patients with obese PCOS in the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine were randomly divided into three groups. The treatment group A was treated with acupoint catgut embedding combined with metformin. The treatment group B was only treated with acupoint catgut embedding. The control group was treated with metformin. The changes of Apelin and adiponectin ( ADP ) levels before and after treatment were compared among the three groups. Results :（1） Post-treatment, Apelin concentrations in the trio of groups were reduced compared to pre-treatment levels（P < 0.05 ） In the control group, Apelin levels exceeded those in both treatment group A and B（P < 0.05 ）, yet the difference between treatment group A and B was not statistically significant (P > 0.05 ). （2）Post-treatment, there was a notable rise in ADP levels among the three groups（P < 0.05 ）, with both treatment group A and B exhibiting significantly elevated levels compared to the control group （P < 0.05 ）， yet the difference between treatment group A and B was not statistically significant(P > 0.05 ). （3）Post-treatment, there was a notable decrease in WHR and BMI levels among the three groups compared to their pre-treatment levels ( P < 0.05 ). There was a notable enhancement in WHR and BMI in treatment group A compared to group B, with group B outperforming the control group (P < 0.05). Conclusion: Drawing from Chongyang theory, treating obese PCOS through acupoint catgut embedding may lower Apelin, WHR, and BMI levels, elevate ADP levels, enhance lipid metabolism in polycystic ovary syndrome, and offer a theoretical foundation for acupoint catgut embedding in treating obese PCOS.

  Key words: Polycystic ovary syndrome; obese; acupoint burrowing; Apein; ADP

  提交时间：2025-06-18

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• 序号	提交日期	编号	操作
  1	2025-03-03	bmr.202506.00046V1	下载

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