通讯作者: 罗胜, tcm2007@163.com

DOI：10.12201/bmr.202504.00057

Mounier-Kuhn syndrome: report of two cases and literature review

• 摘要：【】目的:分析总结Mounier-Kuhn综合征(MKS)的病因及临床特点,以提高对该疾病的认知。方法:报道本院确诊的两例MKS患者,分析其临床特点及影像学表现,并检索CNKI、万方、Pubmed、Web of Science数据库,筛选出高质量MKS病例报告进行系统评价。结果:共纳入240例MKS患者,其病因尚未明确,男性好发,病理特征为气管、主支气管的弹性纤维和平滑肌组织萎缩、纤细,胸部CT、气管镜可见明显的气管支气管扩张,临床表现无特异性。该病缺乏有效治疗手段,目前以抗感染治疗为主,少数可行气管支架置入。结论:MKS是一种罕见呼吸道疾病,与吸烟史无关,可通过胸部CT或气管镜诊断,对于无明显诱因的反复下呼吸道感染应注意本病可能。

  关键词： Mounier-Kuhn综合征; 文献复习

   

  Abstract: 【 】 Objective: To analyze and summarize the etiology and clinical characteristics of Mounier-Kuhn syndrome (MKS), so as to improve the understanding of the disease. Methods: Two cases of MKS diagnosed in our hospital were reported, and their clinical features and imaging findings were analyzed. CNKI, Wanfang, Pubmed, and Web of Science databases were searched to screen out high-quality case reports of MKS for systematic review. Results: A total of 240 patients with MKS were included in this study. The etiology of MKS was not clear, and males were more common. The pathological features were atrophy and slender elastic fibers and smooth muscle tissue of the trachea and main bronchus, and obvious tracheal bronchiectasis was seen on chest CT and bronchoscopy. There is no effective treatment for this disease. At present, anti-infective therapy is the main treatment, and tracheal stent implantation is feasible in a few cases. Conclusions: MKS is a rare respiratory disease, which is not related to smoking history. It can be diagnosed by chest CT or bronchoscopy.

  Key words: Mounier-Kuhn syndrome; Literature review

  提交时间：2025-04-18

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 张卓. 泪囊区淋巴上皮癌1例并文献复习. 2025. doi: 10.12201/bmr.202501.00073

  罗自豪, 耿　刚, 李少军. 儿童肺炎支原体脑炎1例并文献复习. 2024. doi: 10.12201/bmr.202408.00042

  岳晓雪, 赵群. 年轻化疗耐药绒癌病例1例及文献复习. 2024. doi: 10.12201/bmr.202411.00007

  沈艳群, 张露璐. 68例成人噬血细胞综合征患者临床预后分析. 2025. doi: 10.12201/bmr.202502.00008

  郑海娟, 牛晓珊. CCR与代谢综合征及其相关疾病的研究进展. 2025. doi: 10.12201/bmr.202501.00048

  王羚钰, 徐红. 老年骨量-肌量减少性肥胖综合征的治疗进展. 2024. doi: 10.12201/bmr.202411.00064

  陈昕, 杨晓彤, 李一凡, 纪伟. 中医药防治干燥综合征的可视化分析. 2025. doi: 10.12201/bmr.202502.00032

  丁凯玥, 符德元. 老年女性乳腺罗道夫病1例报告并文献复习. 2025. doi: 10.12201/bmr.202503.00076

  郑洁, 张真稳. SGLT2抑制剂对代谢综合征各组分的影响. 2025. doi: 10.12201/bmr.202503.00002

  王玥琳, 蒋运兰, 李乐, 陈红, 王镜, 张梦洁, 白小雨, 武森林. 中国精神分裂症住院患者并发代谢综合征危险因素的Meta分析. 2025. doi: 10.12201/bmr.202504.00071

• 序号	提交日期	编号	操作
  1	2025-02-20	bmr.202504.00057V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论