通讯作者: 谢作流, 93136615@qq.com

DOI：10.12201/bmr.202502.00061

Clinical Application Value of Contrast-Enhanced Ultrasound in the Differential Diagnosis of testicular masses

• 摘要：目的：探讨超声造影在睾丸肿块鉴别诊断中的临床应用价值。方法：收集2014年1月至2024年8月睾丸肿块患者63例，所有患者均行常规超声及超声造影检查，其中55例通过手术切除取得病理结果，8例非肿瘤性患者经临床随访确诊，依据结果，将睾丸肿块分为肿瘤性病变和非肿瘤性病变，其中肿瘤性病变分为良性肿块和恶性肿块，分析常规超声参数：肿块位置，年龄，回声均质性、回声性质，肿块最大直径，血流分级，血清肿瘤标志物：甲胎蛋白（AFP）、人绒毛膜促性腺激素-β亚基（β-HCG），超声造影参数：增强强度，增强时间，增强方式，到达时间（arrival time，AT）、达峰时间（time to peak，TTP）、上升时间（rise time，RT）的统计学意义。结果：在睾丸肿瘤性与非肿瘤性病变鉴别诊断中，肿块最大直径、血流分级、增强时间、增强强度差异有显著统计学意义 (P < 0.05)，肿块位置、年龄、回声均质性、回声性质、血清肿瘤标志物、增强方式、AT、TTP、RT差异无统计学意义(P> 0.05)；睾丸良性肿块和恶性肿块鉴别中，肿块位置、肿块最大直径、回声性质、血流分级、增强时间、增强强度差异有显著统计学意义 (P < 0.05)，年龄、回声均质性、血清肿瘤标志物、增强方式、AP、TTP、RT差异无统计学意义(P > 0.05)。结论：超声造影在睾丸肿块的诊断中可能具有一定参考价值，低增强或无增强、慢进可能是良性病灶的表现。

  关键词： 超声造影; 常规超声; 睾丸肿块; 鉴别诊断

   

  Abstract: Objective: To explore the clinical application value of contrast - enhanced ultrasound in the differential diagnosis of testicular masses.Methods: A total of 63 patients with testicular masses from January 2014 to August 2024 were collected. All patients underwent both conventional ultrasound and contrast - enhanced ultrasound examinations. Among them, pathological results were obtained through surgical resection in 55 cases, and 8 non-tumorous patients were diagnosed through clinical follow-up. According to the results, testicular masses were classified into neoplastic and non - neoplastic lesions. Neoplastic lesions were further divided into benign and malignant masses. The statistical significance of the following parameters was analyzed: Conventional ultrasound parameters included mass location, patient age, echo homogeneity, echo characteristics, maximum diameter of the mass, blood flow grade; Serum tumor markers included serum alpha - fetoprotein (AFP) and beta - subunit of human chorionic gonadotropin (β - HCG); Contrast - enhanced ultrasound parameters included enhancement intensity, enhancement time, enhancement pattern, arrival time (AT), time to peak (TTP), and rise time (RT).Results: In the differential diagnosis between neoplastic and non - neoplastic lesions of the testis, there were significant statistical differences in the maximum diameter of the mass, blood flow grade, enhancement time, and enhancement intensity (P< 0.05), while there were no significant statistical differences in mass location, patient age, echo homogeneity, echo characteristics, serum tumor markers, enhancement pattern, AT, TTP, and RT (P > 0.05). In the differential diagnosis between benign and malignant testicular masses, significant statistical differences were found in mass location, maximum diameter of the mass, echo characteristics, blood flow grade indicators, enhancement time, and enhancement intensity (P < 0.05), while there were no significant statistical differences in patient age, echo homogeneity, serum tumor markers, enhancement pattern, AP, TTP, and RT (P > 0.05). Conclusion: Contrast-enhanced ultrasound may have certain reference value in the diagnosis of testicular masses. Hypo-enhancement or non-enhancement, along with slow enhancement, may be manifestations of benign lesions.

  Key words: Contrast-Enhanced ultrasound; Conventional ultrasound; Testicular masses; Differential diagnosis

  提交时间：2025-02-25

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• 序号	提交日期	编号	操作
  1	2025-01-10	bmr.202502.00061V1	下载

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