通讯作者: 徐新毅, m1888566341@163.com

DOI：10.12201/bmr.202605.00062

An Exploration of the Pathogenesis of Asthma Involving

• 摘要：目的：探讨基于“中焦为枢”理论的“斡旋中焦、通调三焦”法治疗哮病（支气管哮喘）的理论基础与临床应用为目的。方法：系统梳理中焦枢机与三焦气化的理论渊源，阐述“中焦枢机不利，三焦气化失司”在哮病发病中的病理机制，并附典型验案一则以佐证临床疗效。结果：提出哮病病机关键在于中焦斡旋失职，致痰饮内伏、三焦气化壅滞，形成痰瘀互结、风盛挛急之标象。治法当以恢复中焦升降为要，结合上焦宣降、下焦纳气。验案显示该法可改善哮喘控制测试评分及第一秒用力呼气容积，并辅助吸入糖皮质激素降阶梯治疗。结论：“斡旋中焦、通调三焦”法为伴有胃肠功能紊乱的哮病患者提供了整体辨治思路，其机制可能与调节“肠-肺轴”有关，尚需大样本临床研究进一步验证的结论。

  关键词： 哮病,中焦枢机,三焦气化,斡旋治疗; ; ; ; ; ; 

   

  Abstract: Objective: To explore the theoretical basis and clinical application of the method of mediating the middle jiao and unblocking/regulating the sanjiao based on the theory of the middle jiao as the pivot in the treatment of wheezing disorder (bronchial asthma).Methods: The theoretical origins of the middle jiao pivot mechanism and sanjiao qi transformation were systematically reviewed. The pathological mechanism of dysfunction of the middle jiao pivot leading to disordered sanjiao qi transformation in the pathogenesis of wheezing disorder was elucidated. One typical proven case was provided to support clinical efficacy.Results: It is proposed that the key pathogenesis of wheezing disorder lies in the failure of the middle jiao to mediate its pivotal role, leading to latent phlegm-rheum, stagnation of sanjiao qi transformation, and the formation of superficial manifestations such as intermingled phlegm and blood stasis, as well as wind-induced spasmodic constraint. The therapeutic principle should focus on restoring the ascending and descending functions of the middle jiao, while simultaneously facilitating the dispersing and descending of the upper jiao and the qi-receiving function of the lower jiao. The presented case demonstrated that this method can improve the Asthma Control Test score and forced expiratory volume in one second (FEV?), and assist in step-down therapy of inhaled corticosteroids.Conclusion: The method of mediating the middle jiao and unblocking/regulating the sanjiao provides a holistic differentiation and treatment approach for patients with wheezing disorder accompanied by gastrointestinal dysfunction. Its mechanism may be related to regulating the gut-lung axis, though further validation through large-scale clinical studies is required.

  Key words: wheezing; disease, middle; jiao pivot, triple; jiao qi; transformation, regulating; and restoring; therapy

  提交时间：2026-05-18

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2026-03-16	10.12201/bmr.202605.00062V1	下载

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