通讯作者: 岳妍, yueyanyy@163.com

DOI：10.12201/bmr.202512.00044

The Influence of Time Rhythm on the onset of Gastroesophageal Reflux Disease Based on the Theory of Wei Qi Circulation

• 摘要：卫气“昼行于阳，夜行于阴”，时间节律性突出，且具有防御、温煦及固摄等重要功能。本文以“卫气运行理论”为指导，认为卫气运行、卫气功能及昼夜时间节律在胃食管反流病（gastroesophageal reflux disease, GERD）的发病中具有重要作用。卫气由脾胃化生，脾胃健运则卫气充盛，反之卫气运行失常及功能失调可致中焦气机逆乱，胃气上冲，引发本病。本文提出通过调理脾胃枢机、兼顾肝肺升降及调节昼夜节律等多方面综合治疗，最终达到形神共治，提高该病的临床疗效。

  关键词： 胃食管反流病；卫气；时间节律；病机；治疗

   

  Abstract: The wei qi moves in the yang during the day and in the yin at night, with a prominent temporal rhythm, and has important functions such as defense, warmth, and consolidation. Based on the theory of wei qi movement, this article believes that the temporal rhythm plays an important role in the pathogenesis of gastroesophageal reflux disease (GERD). Modern research has confirmed that insufficient sleep and nocturnal eating habits can increase the risk of GERD, and esophageal motility and mucosal repair are regulated by the biological clock. The wei qi is generated by the spleen and stomach. When the spleen and stomach function well, the wei qi is abundant. Conversely, if the movement of the wei qi is abnormal (such as the yang not entering the yin), it can lead to the disorder of the qi movement in the middle burner, the upward rush of stomach qi, and the triggering of GERD. It is proposed to treat GERD under the guidance of the theory of wei qi, while regulating the ascending and descending of the spleen and stomach, taking into account the qi movement of the liver and lungs, and regulating the triple burner; combined with acupuncture and life care, ultimately achieving the balance of form and spirit, in order to improve its clinical efficacy.

  Key words: gastroesophageal reflux disease；wei qi；time rhythm；pathogenesis；therapy

  提交时间：2025-12-15

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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  1	2025-12-02	10.12201/bmr.202512.00044V1	下载

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