通讯作者: 郑彩华, 3227305591@qq.com

DOI：10.12201/bmr.202605.00009

Research Progress on Traditional Chinese Medicine Treatment of Ulcerative Colitis

• 摘要：溃疡性结肠炎是发病机制尚未完全阐明的，以腹痛、腹泻、反复发作的黏液脓血便及里急后重等为临床表现的顽固性肠道炎症性疾病。流行病学数据显示，该病发病率持续攀升，且发病高峰年龄群体呈现年轻化趋势，已严重威胁患者日常生活质量。美沙拉嗪是治疗溃疡性结肠炎的基础用药，其治疗主要集中在肠道黏膜，属于肠道局部作用的抗炎药物。然而，该治疗方式存在局限性，即使溃疡性结肠炎患者的肠道炎症得到缓解，但仍存在长期腹痛、腹泻等症状，机体免疫功能未从根本上改善，导致病情极易复发。溃疡性结肠炎治疗目标是实现临床症状的有效控制与持续缓解，促进受损肠道黏膜的修复再生，预防并发症。本文总结了溃疡性结肠炎中医研究内容，以进一步推动中医诊疗溃疡性结肠炎在临床实践中的应用研究。

  关键词： 溃疡性结肠炎；中医；脾虚; ; 

   

  Abstract: Abstract：Ulcerative colitis (UC) is a stubborn intestinal inflammatory disease with an unclear pathogenesis, characterized by clinical manifestations such as abdominal pain, diarrhea, recurrent mucus and bloody stools, and tenesmus. Epidemiological data show that the incidence of this disease is continuously rising, and the peak age group of onset is showing a trend of younger age, which has seriously threatened the quality of life of patients. Mesalazine is a basic drug for the treatment of ulcerative colitis, and its treatment mainly focuses on the intestinal mucosa, belonging to an anti-inflammatory drug with local intestinal action. However, this treatment method has limitations. Even if the intestinal inflammation of UC patients is relieved, they still have long-term symptoms such as abdominal pain and diarrhea, and the immune function of the body has not been fundamentally improved, leading to an easy recurrence of the disease. The treatment goal of UC is to effectively control and continuously relieve clinical symptoms, promote the repair and regeneration of damaged intestinal mucosa, and prevent complications. This article summarizes the research content of traditional Chinese medicine on UC to further promote the application research of traditional Chinese medicine in the clinical treatment of UC.

  Key words: Ulcerative colitis; Traditional Chinese Medicine; Spleen deficiency

  提交时间：2026-05-02

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2026-04-09	10.12201/bmr.202605.00009V1	下载

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