吴杰, .童雨青, 戴婷. 改良床上脚踏车运动对AECOPD合并呼吸衰竭患者的疗效和安全性影响. 2026. biomedRxiv.202603.00066
改良床上脚踏车运动对AECOPD合并呼吸衰竭患者的疗效和安全性影响
通讯作者: 吴杰, docwujie2004@aliyun.com
DOI:10.12201/bmr.202603.00066
The efficacy and safety impact of the modified bed-mounted exercise bike program on patients with AECOPD and respiratory failure
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摘要:【摘要】 目的 观察AECOPD合并呼吸衰竭患者应用无创呼吸机联合改良床上脚踏车运动的疗效影响。方法 回顾性研究,收集2023年1月~2024年12月在作者单位接受治疗患者的病历资料,根据患者不同疗法分为观察组与对照组。2组患者按照指南规范接受常规治疗,对照组同时间断使用NIV治疗,观察组联合改良床上脚踏车运动治疗。比较2组患者的肺功能、血气指标、日常生活活动能力、双上肢及下肢肌群肌力和不良反应等。结果 治疗后2组患者PaCO2水平相比治疗前降低,PEF、FEV1、FEV1/FEV比值、PaO2水平、Barthel指数相比治疗前升高;且观察组PaCO2水平、无创通气时间、住院时间低于对照组,PEF、FEV1、FEV1/FEV比值、PaO2水平、Barthel指数高于对照组(P<0.05)。观察组与对照组患者管路脱落、皮肤损伤、心律失常发生率比较无显著差异(P>0.05)。观察组气管插管率低于对照组(P<0.05)。结论 NIV联合改良床上脚踏车运动可改善AECOPD合并呼吸衰竭患者的肺功能和血气指标,降低无创通气时间和住院时间,提高双上肢及下肢肌群肌力水平。
Abstract: Abstract?Objective? Observation on the therapeutic effect of using non-invasive ventilator combined with modified bed-mounted pedal exercise in patients with AECOPD complicated with respiratory failure.?Method A retrospective study was conducted, collecting the medical records of patients who received treatment at the authors institution, from January 2023 to December 2024. The patients were divided into the observation group and the control group based on different treatment methods. Both groups of patients received routine treatment according to the guidelines, while the control group intermittently used NIV treatment at the same time. The observation group combined with modified bed-mounted pedal exercise therapy. The pulmonary function, blood gas indicators, daily living activity ability, muscle strength of both upper limbs and lower limbs, and adverse reactions of the two groups of patients were compared.??Results After treatment, the PaCO2 levels of the two groups of patients decreased compared to before treatment, while the PEF, FEV1, FEV1/FEV ratio, PaO2 levels, and Barthel index increased compared to before treatment. Moreover, the PaCO2 levels, non-invasive ventilation time, and hospitalization time in the observation group were lower than those in the control group, while the PEF, FEV1, FEV1/FEV ratio, PaO2 levels, and Barthel index were higher than those in the control group (P<0.05). There was no significant difference in the incidence of pipeline detachment, skin injury, and arrhythmia between the observation group and the control group (P>0.05). The tracheal intubation rate in the observation group was lower than that in the control group (P<0.05).?Conclusion The combined modified bed-mounted exercise bike program can improve the lung function and blood gas indicators of patients with AECOPD and respiratory failure, reduce the duration of non-invasive ventilation and hospital stay, and enhance the muscle strength of both upper and lower limb groups.
Key words: Acute?exacerbation?of?chronic?obstructive?pulmonary?disease; ?Respiratory?failure; ?Cycling?exercise; ?Blood?gas?analysis; ?Barthel?index提交时间:2026-03-18
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序号 提交日期 编号 操作 1 2026-01-29 10.12201/bmr.202603.00066V1
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