许扬坡, 蓝宜盛, 郭安妮, 詹瑷榕. 穴位贴敷对肺肾气虚型COPD稳定期患者运动耐力及心肺功能的临床疗效观察. 2026. biomedRxiv.202602.00020
穴位贴敷对肺肾气虚型COPD稳定期患者运动耐力及心肺功能的临床疗效观察
通讯作者: 詹瑷榕, 793962241@qq.com
DOI:10.12201/bmr.202602.00020
Observation on the Clinical Efficacy of Acupoint Application on Exercise Endurance and Cardiopulmonary Function in Patients with Stable COPD of Lung and Kidney Qi Deficiency Type
Corresponding author: Zhan Airong, 793962241@qq.com
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摘要:目的:观察穴位贴敷在肺肾气虚型慢性阻塞性肺疾病(COPD)稳定期患者运动耐力及心肺功能的影响。方法:将80例肺肾气虚型COPD稳定期患者按照随机数字表法随机分为对照组(40例)和观察组(40例)。对照组采取抗感染、止咳化痰平喘等西医对症治疗,观察组在对照组的基础上实施穴位贴敷,隔日治疗1次,每次贴1~2小时,连续贴敷7次为一疗程,共治疗3个疗程。在治疗前及每个疗程结束后分别统计两组患者6分钟步行距离(6MWD)、第一秒用力呼气容积百分比(FEV1%)、慢性阻塞性肺疾病疗效满意度问卷修订版(mESQ-COPD)评分;在治疗前及全部疗程结束后计算中医证候评分。结果:治疗后,两组患者6MWT、FEV1%均较治疗前升高(P均<0.05),且观察组高于对照组(P均<0.05);两组患者mESQ-COPD评分和中医证候评分均较治疗前降低(P均<0.05),且观察组低于对照组(P均<0.05)。急性加重方面,在整个研究期间,观察组发生急性加重的患者少于对照组,但两组差异无统计学意义(P>0.05)。结论:穴位贴敷作为药物治疗的补充,可以有效改善肺肾气虚型COPD稳定期患者的运动耐力和心肺功能,提高生存质量,疗效明显,为穴位贴敷疗法治疗慢性迁延难愈的肺系疾病提供了循证医学依据。
Abstract: Objective: To observe the effects of acupoint application on exercise tolerance and cardiopulmonary function in patients with chronic obstructive pulmonary disease (COPD) of the lung-kidney qi deficiency type during the stable phase. Methods: Eighty patients with stable chronic obstructive pulmonary disease (COPD) of lung-kidney qi deficiency type were randomly assigned to a control group (n=40) and an observation group (n=40) using a random number table. The control group received symptomatic Western medical interventions including anti-infection, cough suppression, expectoration promotion, and asthma relief. The observation group, in addition to the above-mentioned treatment for the control group, was administered acupoint application therapy: once every other day, with each application lasting 1–2 hours. A treatment course consisted of 7 consecutive applications, and a total of 3 courses were completed.Before treatment and at the end of each course, the 6-minute walking distance (6MWD), percentage of forced expiratory volume in the first second (FEV?%), and scores of the modified COPD Efficacy Satisfaction Questionnaire (mESQ-COPD) were assessed and recorded for both groups. The Traditional Chinese Medicine (TCM) syndrome scores were evaluated before treatment and after the completion of all treatment courses.Results: After treatment, both groups showed increased 6MWD and FEV1% compared to pre-treatment levels (P <0.05), with the observation group showing higher improvements than the control group (P <0.05). Both groups exhibited reduced mESQ-COPD scores and TCM syndrome scores compared to pre-treatment levels (P <0.05), with the observation group showing lower improvements than the control group (P <0.05). Regarding acute exacerbations, during the entire study period, fewer patients in the observation group experienced acute exacerbations compared to the control group, but the difference between the two groups was not statistically significant (P>0.05). Conclusion: Acupoint application, as a supplement to pharmacological treatment, can effectively improve exercise tolerance and cardiopulmonary function in patients with stable COPD of lung-kidney qi deficiency type, enhance quality of life, and demonstrate significant therapeutic efficacy. This provides evidence-based medical support for the application of acupoint therapy in treating chronic refractory lung diseases.
Key words: : Chronic obstructive pulmonary disease (COPD); Lung-kidney qi deficiency type; Acupoint application; Cardiopulmonary endurance提交时间:2026-02-06
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序号 提交日期 编号 操作 1 2026-01-28 10.12201/bmr.202602.00020V1
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