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DOI: 10.12201/bmr.202504.00050

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  Abstract: Objective This study aims to retrospectively analyze the clinical data of patients with thyroid cancer combined with primary hyperparathyroidism at Beijing Friendship Hospital. The objective is to explore the disease characteristics, diagnostic processes, and surgical treatment strategies for these patients. Through this analysis, the study seeks to enhance surgeons understanding of this condition and provide scientific evidence for developing more precise and effective treatment plans, ultimately improving patient outcomes.Methods Retrospective case analysis was performed on patients with thyroid cancer complicated with primary hyperparathyroidism who underwent surgical treatment from January 2016 to January 2022 in our hospital, and some thyroid cancer patients were randomly selected as the control group. The operation time, blood loss, hospital stay, and complications were compared between the two groupsResults A total of 3686 patients with thyroid cancer were included in the study, including 22 patients with primary hyperparathyroidism.44 thyroid cancer patients were randomly selected as the control group. There was no statistical difference in the preoperative basic line such as the age, gender, BMI and the diameter of thyroid cancer. Both groups underwent surgery, and the thyroid cancer patients with primary hyperparathyroidism group had a longer operation time than the thyroid cancer patient group (p<0.0001), but there was no statistical difference in intraoperative blood loss, hospital stay, and postoperative complications.Conclusion The coexistence of thyroid cancer with primary hyperparathyroidism (PHPT) increases the complexity of treatment. However, with thorough preoperative diagnosis and well-planned surgical strategies, the risks of reoperation and postoperative complications can be effectively reduced, thereby improving patient outcomes.

  Key words: Thyroid; cancer,Primary; hyperparathyroidism, Surgical; Treatment,Disease; Characteristics,Diagnostic; Methods

  Submit time: 16 April 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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