通讯作者: 杜安然, 1042673053@qq.com

DOI：10.12201/bmr.202504.00050

• 摘要：目的 本研究旨在通过回顾性分析北京友谊医院甲状腺癌合并原发性甲状旁腺功能亢进患者的临床资料，深入探讨此类患者的发病特点、诊断流程及外科治疗策略，以期提高外科医生对此类疾病的认识，并为制定更加精准、有效的治疗方案提高科学依据，从而改善患者预后。方法 对我院2016年1月至2022年1月甲状腺癌合并原发性甲状旁腺功能亢进行手术治疗患者进行回顾性病例分析，随机抽取部分甲状腺癌患者作为对照组。比较甲状腺癌合并原发性甲状旁腺功能亢进和单纯甲状腺癌两组患者的手术时间、出血量、住院时间、并发症发生情况等。结果 共有3686例甲状腺癌患者纳入研究，其中合并原发性甲状旁腺功能亢进患者 22例，随机挑选44例单纯甲状腺癌患者作为对照组，两组患者年龄、性别比例、BMI、单侧比例、甲状腺癌最大直径等术前基本资料无统计学差异。两组患者均进行了手术，其中甲状腺癌合并原发性甲状旁腺功能亢进患者组手术时间长于单纯甲状腺癌患者组 (p<0.0001) ，但术中出血量、住院时间、术后并发症等方面无统计学差异。结论 甲状腺癌合并PHPT增加了治疗复杂性，但是通过充分的术前诊断以及合理的外科治疗策略，可有效降低二次手术及术后并发症风险，改善患者预后。

  关键词： 甲状腺癌,原发性甲状旁腺功能亢进,手术治疗,发病特点,诊断方法; ; ; ; ; 

   

  Abstract: Objective This study aims to retrospectively analyze the clinical data of patients with thyroid cancer combined with primary hyperparathyroidism at Beijing Friendship Hospital. The objective is to explore the disease characteristics, diagnostic processes, and surgical treatment strategies for these patients. Through this analysis, the study seeks to enhance surgeons understanding of this condition and provide scientific evidence for developing more precise and effective treatment plans, ultimately improving patient outcomes.Methods Retrospective case analysis was performed on patients with thyroid cancer complicated with primary hyperparathyroidism who underwent surgical treatment from January 2016 to January 2022 in our hospital, and some thyroid cancer patients were randomly selected as the control group. The operation time, blood loss, hospital stay, and complications were compared between the two groupsResults A total of 3686 patients with thyroid cancer were included in the study, including 22 patients with primary hyperparathyroidism.44 thyroid cancer patients were randomly selected as the control group. There was no statistical difference in the preoperative basic line such as the age, gender, BMI and the diameter of thyroid cancer. Both groups underwent surgery, and the thyroid cancer patients with primary hyperparathyroidism group had a longer operation time than the thyroid cancer patient group (p<0.0001), but there was no statistical difference in intraoperative blood loss, hospital stay, and postoperative complications.Conclusion The coexistence of thyroid cancer with primary hyperparathyroidism (PHPT) increases the complexity of treatment. However, with thorough preoperative diagnosis and well-planned surgical strategies, the risks of reoperation and postoperative complications can be effectively reduced, thereby improving patient outcomes.

  Key words: Thyroid; cancer,Primary; hyperparathyroidism, Surgical; Treatment,Disease; Characteristics,Diagnostic; Methods

  提交时间：2025-04-16

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2025-02-24	bmr.202504.00050V1	下载

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