• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Meta-analysis of the effects of ERAS in the perioperative period in patients with heart valve disease

Corresponding author: Chen Yuan, 28837445@qq.com
DOI: 10.12201/bmr.202410.00008
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Objective Evaluate the perioperative application of Enhanced Recovery After Surgery (ERAS) in patients with valvular heart disease systematically through Meta-analysis. Methods We performed an extensive search for randomized controlled trials investigating the use of ERAS protocols during the perioperative period in patients with heart valve disease. Eight databases were searched, including China Knowledge Network, WanFang Database, and China Biomedical Literature Database, spanning literature from January 2015 to June 2024.Two researchers conducted an independent review of the literature and extracted pertinent data. We conducted a Meta-analysis using RevMan 5.4 software on the selected studies. Results We analyzed a total of 26 studies, involving 2,664 participants. The Meta-analysis revealed that patients in the ERAS group experienced a significant reduction in the postoperative time to first defecation and bowel movement, as well as a quicker time to first ambulation, reduced hospital stay duration, and fewer postoperative complications. Additionally, there was a notable improvement in the patients quality of life. Conclusion The application of ERAS protocols in patients undergoing heart valve surgery markedly improves recovery, lowers the frequency of complications, and improves overall standard of living. The above conclusions still need to be further verified on the basis of high-quality clinical trials.

    Key words: Enhanced Recovery After Surgery; Heart Valve Diseases; Perioperative Period; Meta analysis

    Submit time: 5 October 2024

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  • ID Submit time Number Download
    1 2024-07-19

    bmr.202410.00008V1

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Chen Yuan, Chen Shiqi, Zhang Rongxiang, Zhu Chenyang. Meta-analysis of the effects of ERAS in the perioperative period in patients with heart valve disease. 2024. biomedRxiv.202410.00008

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