Research Progress on Lumbar Disc Herniation with Modic Changes

Corresponding author: qinyi, qinyi025@163.com

DOI: 10.12201/bmr.202603.00112

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  Abstract: Lumbar disc herniation (LDH) is a common spinal condition whose incidence gradually increases with age. Modic changes (MCs), as a frequent imaging manifestation of the vertebral endplate, have attracted significant attention in the context of LDH. This article summarizes the classification and progression, pathophysiological mechanisms, and the relationship between MCs and LDH, while also briefly discussing related treatment strategies. The aim is to provide a reference for the future diagnosis and management of LDH accompanied by Modic changes.

  Key words: Lumbar Disc Herniation; Modic Changes; Pathogenesis; Treatment Strategies; Low Back Pain

  Submit time: 25 March 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2026-02-09	10.12201/bmr.202603.00112V1	Download

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