通讯作者: 孔祥耀, xykong0574@126.com

DOI：10.12201/bmr.202506.00037

Efficacy Analysis of Two Different Endovascular Thrombectomy Approaches for Treating Early-Stage Lower Extremity Deep Vein Thrombosis: A Single-Center Retrospective Study

• 摘要：目的:比较分析AngioJet机械性血栓清除与大腔导管抽吸系统治疗早期下肢深静脉血栓的临床疗效及安全性差异。方法:回顾性分析2020年1月至2024年10月宁波市医疗中心李惠利医院收治的88例接受机械血栓清除治疗的下肢深静脉血栓患者。根据手术方式分为AngioJet组(A组)和负压大腔导管组(B组),比较两组围术期指标(手术时长、住院时长)、血栓清除效果(即刻清除率、最终清除率)及术后并发症发生情况。结果:两组基线资料具有可比性(P>0.05)。手术成功率100%,两组患者在住院时长、手术时长、术后清除率、最终清除率上差异无统计学意义。并发症方面,A组血尿发生率显著高于B组,B组3例发生穿刺部位出血。结论:两种机械血栓清除方式在早期LEDVT治疗中均展现良好疗效,AngioJet机械血栓清除系统需警惕溶血相关肾损伤风险,建议加强围术期水化及肾功能监测；负压大腔导管存在穿刺点出血、操作繁琐、损伤静脉瓣膜等不足,经皮机械性血栓清除装置仍需不断改进创新。

  关键词： 机械性血栓清除,深静脉血栓

   

  Abstract: Objective: To compare and analyze the clinical efficacy and safety differences between AngioJet mechanical thrombectomy and large bore catheter aspiration systems in treating early deep vein thrombosis in the lower limbs. Methods: A retrospective analysis was conducted on 88 patients with deep vein thrombosis in the lower limbs who received mechanical thrombectomy treatment at Li Hui Li Hospital, Ningbo Medical Center from January 2020 to October 2024. The patients were divided into two groups based on surgical method: Group AngioJet (A group) and Group B (negative pressure large bore catheter group). The perioperative indicators (surgical duration, hospital stay), thrombus clearance outcomes (immediate clearance rate, final clearance rate), and postoperative complications were compared between the two groups. Results: The baseline data of both groups were comparable (P>0.05). The success rate of surgery was 100%, and there were no statistically significant differences in hospital stay, surgical duration, postoperative clearance rate, or final clearance rate between the two groups. In terms of complications, the incidence of hematuria in Group A was significantly higher than in Group B, with 3 cases of puncture site bleeding in Group B. Conclusion: Both mechanical thrombectomy methods demonstrated good therapeutic effects in early LEDVT. The AngioJet mechanical thrombectomy system requires vigilance against the risk of hemolysis-related kidney injury, and it is recommended to enhance perioperative hydration and renal function monitoring. Large-bore negative pressure catheters have shortcomings such as puncture site bleeding, cumbersome operation, and venous valve damage. Percutaneous mechanical thrombectomy devices still require continuous improvement and innovation.

  Key words: percutaneous mechanical thrombectomy, deep vein thrombosis

  提交时间：2025-06-16

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2025-06-03	bmr.202506.00037V1	下载

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