通讯作者: 刘振, 155350022@qq.com

DOI：10.12201/bmr.202412.00019

Clinical Observation of Jiawei Sanpian Decoction（加味散偏汤） in the Treatment of Liver Stagnation and Blood Stasis Type Tension Headache

• 摘要：目的：观察加味散偏汤治疗肝郁血瘀型紧张型头痛(TTH)的临床疗效。方法：采用随机对照双盲试验设计,纳入2021年4月至2022年11月就诊于北京市第一中西医结合医院门诊及病房的肝郁血瘀型TTH患者90例,观察组采用加味散偏汤颗粒剂联合布洛芬胶囊治疗,对照组则予加味散偏汤颗粒剂模拟剂联合布洛芬胶囊治疗,28天为一个疗程。研究过程中脱落3例患者,共计有87例患者进行统计分析,其中观察组44例,对照组43例,比较2组患者疼痛VAS评分积分、中医症状积分及有效率。结果：两组患者疼痛积分、症状积分治疗前比较无明显统计学差异(P=0.661,P=0.654),治疗后两组疼痛积分、症状积分均较治疗前明显下降(P＜0.001),其中观察组疼痛积分、症状积分较对照组下降更明显(P=0.001,P=0.014)。治疗后,观察组患者有效率(90.90%)明显高于对照组的有效率(69.77%)(P=0.013)。结论：联合加味散偏汤治疗能够降低肝郁血瘀型TTH患者的疼痛VAS评分,改善患者临床症状,提升临床有效率,优于单纯西医治疗,值得临床推广应用。

  关键词： 紧张型头痛; 加味散偏汤; 肝郁血瘀; 临床观察; ; 

   

  Abstract: ABSTRACT Objective To observe the clinical efficacy of Jiawei Sanpian Decoction in the treatment of liver stagnation and blood stasis type tension headache (TTH). Methods A randomized controlled double-blind trial design was used to include 90 patients with hepatic stagnation and blood stasis TTH who were admitted to the outpatient clinics and wards of Beijing First Hospital of Integrated Traditional Chinese and Western Medicine from April 2021 to November 2022, and the treatment group was treated with Jiawei Sanpian Decoction granules combined with ibuprofen capsules, and the control group was treated with Jiawei Sanpian Decoction granules simulant combined with ibuprofen capsules for 28 days. A total of 87 patients were statistically analyzed, including 44 patients in the treatment group and 43 patients in the control group, and the pain VAS score score, TCM symptom score and effective rate of the two groups were compared. Results There was no significant difference in pain score and symptom score between the two groups before treatment (P=0.661，P=0.654), and the pain score and symptom score in the two groups decreased significantly after treatment (P＜0.001), and the pain score and symptom score in the treatment group decreased more significantly than that in the control group (P=0.001，P=0.014), and the difference was statistically significant. After treatment, the effective rate of patients in the treatment group (90.90%) was significantly higher than that in the control group (69.77%) (P=0.013). Conclusion Combined with Jiawei Sanpian Decoction treatment, it can reduce the pain VAS score of patients with liver stagnation and blood stasis TTH, improve the clinical symptoms of patients, and enhance the clinical effective rate, which is better than Western medicine treatment alone, and is worthy of clinical promotion and application.

  Key words: Tension-type; headache, Jiawei; Sanpian Decoction(加味散偏汤), hepatic; stagnation and; blood stasis, Clinical; observations

  提交时间：2024-12-06

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• 序号	提交日期	编号	操作
  1	2024-11-16	bmr.202412.00019V1	下载

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