贾玉梅, 李阳. “阳杀阴藏”理论在肺癌治疗中的应用探析. 2026. biomedRxiv.202608.00054
“阳杀阴藏”理论在肺癌治疗中的应用探析
通讯作者: 李阳, liyang@hnca.org.cn
DOI:10.12201/bmr.202608.00054
An Analysis of the Application of the “Yang Kills, Yin Hides” Theory in the Treatment of Lung Cancer
Corresponding author: Li Yang, liyang@hnca.org.cn
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摘要:摘要:肺癌之恶性增殖,可归于“少阳相火妄动”所致,“壮火食气”驱动的“炎癌转化”是其核心病机。本文基于《素问·天元纪大论》“阳杀阴藏”理论,结合肺癌“肺失肃降、阳不敛阴”的病理特点,提出治疗之核心在于恢复肺金肃降之能,使浮越之阳得以敛降归藏。临证当以“阳杀”之法折其壮火,以“扶正”充养正气,以“祛邪”化解“痰瘀”之胶结,使伏藏之癌毒不复“妄动”,并根据疾病不同阶段动态调整攻、调、养三法之权重,形成“初则直折壮火、中则攻补并重、末则养正缓攻”的分期辨治方案,从而达到“带瘤生存”的治疗目标。本文总结肺癌治疗的临证经验,并附典型医案一则,其影像学与肿瘤标志物的动态变化为上述理论提供了临床佐证。
Abstract: Abstract: The malignant proliferation of lung cancer can be attributed to the “uncontrolled movement of the Shao Yang phase fire”; the “transformation of inflammation into cancer,” driven by “intense fire consuming qi,” constitutes its core pathogenesis. Based on the theory of “Yang Slaying Yin and Storing” from the Su Wen: Great Treatise on the Origin of Heaven, and in conjunction with the pathological characteristics of lung cancer—namely, “the lung’s failure to perform its descending and purifying functions, and Yang’s failure to contain Yin”—this paper proposes that the core of treatment lies in restoring the lung’s (Metal) ability to descend and purify, thereby enabling the floating and excessive Yang to be contained, descended, and returned to its proper storage. In clinical practice, the method of “Yang Slaying” should be employed to subdue the raging fire, while “Supporting the Righteous Qi” is used to nourish and replenish the body’s vital energy, and “expelling pathogens” to resolve the congealed “phlegm and blood stasis,” thereby preventing the latent cancerous toxins from “acting recklessly.” Furthermore, the emphasis on the three therapeutic methods—attacking, regulating, and nourishing—should be dynamically adjusted according to the different stages of the disease, forming a stage-specific treatment plan characterized by “directly subduing the raging fire in the early stage, giving equal weight to attacking and tonifying in the middle stage, and nourishing the righteous Qi while gradually reducing the intensity of treatment in the late stage,” thereby achieving the therapeutic goal of “living with the tumor.” This article summarizes clinical experience in the treatment of lung cancer and includes a typical case report; the dynamic changes in imaging findings and tumor markers provide clinical evidence supporting the aforementioned theory.
Key words: Yang-killing and Yin-hiding; lung cancer; excessive fire consuming qi; tumor microenvironment; strengthening the healthy and expelling the pathogenic提交时间:2026-08-31
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序号 提交日期 编号 操作 1 2026-07-22 10.12201/bmr.202608.00054V1
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