通讯作者: 徐陆周, 1343141367@qq.com

DOI：10.12201/bmr.202511.00044

Exploring the Pathogenesis and Treatment Strategies of Gastric Inflammation-Cancer Transformation Based on the Theory of Where There is Lingering Masses, There Must Be Latent Yang

• 摘要：“炎癌转化”是胃癌发生的关键机制,炎症微环境的长期存在导致了肿瘤的产生,现阶段西医缺乏对其干预的有效治疗。本文结合“痞坚之处,必有伏阳”理论及现代医学研究,认为“伏阳”是胃“炎癌转化”的发病基础,导致了气、湿、痰、瘀、毒等多种病理产物的产生和胶结,使得炎症微环境长期存在,最终形成肿瘤微环境,发为“痞坚”。故治疗上应紧扣“伏阳”,以清阳、宣阳、阴中求阳、温阳为基本大法,进行辨证论治,以达到去病理之“伏阳”,壮生理之阳气的作用,为防治胃“炎癌转化”提供新思路。

  关键词： “痞坚之处，必有伏阳”; 胃“炎癌转化”; 理论探讨

   

  Abstract: Inflammation-cancer transformation is a key mechanism in the development of gastric cancer. The persistent presence of an inflammatory microenvironment drives tumorigenesis, for which Western medicine currently lacks effective interventions. Integrating the theory of Where there is lingering masses, there must be latent Yang with modern medical research, this paper posits that Latent Yang serves as the pathogenic foundation of gastric inflammation-cancer transformation. It leads to the production and aggregation of various pathological factors such as Qi stagnation, dampness, phlegm, blood stasis, and toxins, resulting in the sustained inflammatory microenvironment that eventually evolves into a tumor microenvironment, manifesting as lingering masses. Therefore, treatment should focus on Latent Yang, employing core methods such as clearing Yang, diffusing Yang, seeking Yang within Yin, and warming Yang, tailored through syndrome differentiation. The aim is to eliminate pathological Latent Yang while strengthening physiological Yang Qi, thereby providing new insights for preventing and treating gastric inflammation-cancer transformation.

  Key words: Where there is lingering masses, there must be latent Yang; Gastric inflammation-cancer transformation; Theoretical exploration

  提交时间：2025-11-18

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• 序号	提交日期	编号	操作
  1	2025-10-14	10.12201/bmr.202511.00044V1	下载

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