通讯作者: 刘晓瑜, 110263214@qq.com

DOI：10.12201/bmr.202608.00025

• 摘要：摘要：目的：基于肺肠轴理论，初步探索电针疗法干预对痰热腑实型轻症脑卒中相关性肺炎向重症进展的阻断效果，分析其对肠道功能紊乱的改善作用及全身炎症反应的抑制效应。方法：采用单中心探索性对照预实验设计，选取本院100例PSI Ⅲ级痰热腑实轻症SAP患者，随机分为对照组（常规西医治疗）、治疗组（常规西医治疗+电针疗法），每组各50例。主要观察指标为重症转化率；次要指标含抗生素使用时长、10d复发率、痰热腑实积分、肠道恢复时间；于治疗前、第3、7天、疗程末检测CPIS、CRP、PCT，对比两组疗效。结果：治疗组重症转化率8.0%，低于对照组24.0%，组间差异有统计学意义（P＜0.05）；治疗组抗生素使用时长更短、中医证候与肠道功能恢复更快，炎症指标改善幅度优于对照组（P＜0.05）；10 d复发率仅数值低于对照组，组间差异无统计学意义（P=0.065）。结论：本预试验初步提示电针联合西医可能降低轻症SAP重症转化风险，缩短抗感染周期，其确切疗效仍待多中心、大样本正式RCT验证。

   

  Abstract: Abstract：Objective: Based on the gut-lung axis theory, to preliminarily explore the blocking effect of electroacupuncture on the progression from mild stroke-associated pneumonia (SAP) with phlegm-heat fu-excess syndrome to severe disease, and to analyze its efficacy in alleviating intestinal dysfunction and suppressing systemic inflammatory response.Methods: A single-center exploratory controlled pilot trial was conducted. A total of 100 mild SAP patients with PSI grade Ⅲ and phlegm-heat fu-excess syndrome admitted to our hospital were enrolled and randomly assigned to a control group (routine Western medicine treatment) and a treatment group (routine Western medicine combined with electroacupuncture), with 50 cases in each group. The primary outcome indicator was the severe transformation rate. Secondary indicators included the duration of antibiotic administration, 10-day recurrence rate, phlegm-heat fu-excess syndrome score and intestinal function recovery time. CPIS, CRP and PCT were detected before treatment, on the 3rd day, the 7th day and at the end of the treatment course to compare the clinical efficacy between the two groups.Results: The severe transformation rate was 8.0% in the treatment group, which was lower than 24.0% in the control group, with a statistically significant intergroup difference (P＜0.05). The treatment group had shorter antibiotic administration duration, faster recovery of TCM syndromes and intestinal function, and more obvious improvement in inflammatory markers compared with the control group (all P＜0.05). The 10-day recurrence rate was numerically lower in the treatment group without statistically significant difference (P=0.065).Conclusion: This pilot trial preliminarily suggests that electroacupuncture combined with Western medicine may reduce the risk of severe transformation and shorten the anti-infection course in patients with mild SAP. Its definite therapeutic effect needs to be verified by multi-center, large-sample formal RCTs.

  提交时间：2026-08-12

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 苏照海, 曹竣, 杨荣源, 刘擎, 刘青艳. 哮喘相关性肺炎与心力衰竭因果关系的双向两样本孟德尔随机化研究. 2025. doi: 10.12201/bmr.202509.00016

  肖岑昕, 黄旭日, 赵伟丹. 血清铁在中老年社区获得性肺炎疾病识别的相关性评估. 2025. doi: 10.12201/bmr.202501.00002

  于卉, 孙世竹. 基于“肺肠相关”与现代免疫机理探讨肺结节的中医治疗. 2026. doi: 10.12201/bmr.202603.00116

  张云海, 柳松涛, 陈新禧, 何天凤, 张诗曼, 邓梦华. 益气通腑方治疗脓毒症急性胃肠损伤气虚腑实证的临床观察. 2026. doi: 10.12201/bmr.202607.00007

  p>何海玲, 陆建良, 冯媛, 卢艳玲. 儿童重症肺炎支原体肺炎的临床特点分析. 2025. doi: 10.12201/bmr.202505.00038

  黄鹏, 黄寨, 覃一钰, 陈泽山, 张云利. 穴位贴敷联合机械辅助排痰对重症肺炎患者预后的影响. 2026. doi: 10.12201/bmr.202607.00030

  李颖, 王晓妃, 陆圣威, 董丹妮, 张景峰, 郑建军. 免疫检查点抑制剂相关性肺炎CT表现与临床特点分析. 2024. doi: 10.12201/bmr.202407.00008

  曹馨月, 何刚. 大黄及其类方干预脑卒中的基础研究进展. 2026. doi: 10.12201/bmr.202601.00051

  时小淋, 汤冬静, 吴美慧. 儿童肺炎支原体支气管肺炎和大叶性肺炎的相关危险因素分析. 2025. doi: 10.12201/bmr.202507.00035

  马亚鑫, 朱晓伟, 李淑琼, 李云翔, 孙永红. 儿童重症肺炎支原体肺炎早期预测的研究进展. 2025. doi: 10.12201/bmr.202504.00073

• 序号	提交日期	编号	操作
  1	2026-07-06	10.12201/bmr.202608.00025V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论