通讯作者: 王玉梅, wangmeimei654@126.com

DOI：10.12201/bmr.202604.00088

The effect of Xiaoxianxiong decoction combined with Maxing Shigan decoction and bronchoscopic bronchoalveolar lavage on inflammatory indicators and lung function in patients with bronchiectasis and infection

• 摘要：目的:分析针对支气管扩张伴感染患者给予小陷胸汤合麻杏石甘汤联合支气管镜肺泡灌洗治疗对其炎症指标、肺功能等的影响。方法:抽取2024年8月-2025年3月赣州市中医院收治的80例支气管扩张伴感染患者，采用随机数字表法分为对照组、治疗组各40例，分别给予常规治疗联合支气管镜肺泡灌洗治和在上述基础上给予小陷胸汤合麻杏石甘汤治疗。对比两组患者中医证候积分（咳嗽、咳痰、发热、胸闷、咯血）、炎症指标、肺功能、安全性、临床疗效。结果:治疗后治疗组中医症候积分、炎症指标水平低于对照组，差异有统计学意义（P＜0.05）；治疗后治疗组肺功能高于对照组，差异有统计学意义（P＜0.05）；治疗后治疗组患者临床疗效高于对照组（P＜0.05），差异有统计学意义；两组患者治疗期间，进行随访观察，均未出现支气管镜肺泡灌洗不良事件以及药物不良反应。结论:小陷胸汤合麻杏石甘汤联合支气管镜肺泡灌洗治疗方案，有效改善患者临床症状、抑制其炎症反应，并有效提高患者肺功能，临床效果显著，具有较高安全性。

  关键词： 小陷胸汤合麻杏石甘汤; 支气管镜肺泡灌洗; 支气管扩张伴感染; 炎症指标; 肺功能

   

  Abstract: 【Abstract】Objective:To analyze the impact of Xiaoyanxiong Decoction combined with Maxing Shiganoction and bronchoscopy alveolar lavage therapy on inflammation indicators and pulmonary function in patients with bronchiectasis and infection.Methods:A total of 80 patients with bronchiectasis complicated by infection admitted to Ganzhou Hospital of Traditional Chinese Medicine from August 2024 to March 2025 were selected and randomly divided into a control group and a treatment group (40 cases each) using a random number table method. The control group received conventional treatment combined with bronchoscopic alveolar lavage, while the treatment group received Xiaotianxian Decoction combined with Maxing Shigan Decoction on this basis. The two groups were compared in terms of traditional Chinese medicine (TCM) syndrome scores (cough, sputum production, fever, chest tightness, hemoptysis), inflammatory indicators , pulmonary function , safety, and clinical efficacy.Results:After treatment, the TCM syndrome scores and inflammatory indicator levels in the treatment group were lower than those in the control group, with statistically significant differences (P<0.05). Pulmonary function indicators in the treatment group were higher than those in the control group, with statistically significant differences (P<0.05). The clinical efficacy of the treatment group was higher than that of the control group (P<0.05), with a statistically significant difference. During the treatment period, follow-up observation showed no adverse events related to bronchoscopic alveolar lavage or drug adverse reactions in either group.Conclusion: Xiaoyanxiong Decction combined with Maxing Shigan Decoction and bronchoscopy alveolar lavage therapy can effectively improve the clinical symptoms of patients, inhibit their inflammatory response, and improve the pulmonary function of patients, with significant clinical effects and high safety.

  Key words: Xiaoyanxiong Decoction combined with Maxing Shiganoction; bronchoscopy alveolar lavage; bronchiectasis with infection; inflammation indicators; pulmonary function

  提交时间：2026-04-10

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 刘松, 李渊, 马建岭, 史利卿, 郝素英, 王丽云, 罗景舒, 郭兆迪. 清醒镇静技术在支气管镜检查中的应用研究进展. 2024. doi: 10.12201/bmr.202409.00030

  吴思乐, 曾韵萍, 刘晖, 龚璇, 陆丹红. 耳尖刺络放血联合柴葛解肌汤治疗急性上呼吸道病毒感染性发热的疗效观察. 2026. doi: 10.12201/bmr.202602.00089

  李森强, 冯琦, 宋才渊, 李伦辛. 张氏清热消瘀汤联合VSD治疗胫腓骨开放性骨折创面感染疗效及安全性. 2024. doi: 10.12201/bmr.202410.00023

  时小淋, 汤冬静, 吴美慧. 儿童肺炎支原体支气管肺炎和大叶性肺炎的相关危险因素分析. 2025. doi: 10.12201/bmr.202507.00035

  徐默雨, 王雨蝶, 李玉勤, 卢红艳, 常明. 维生素D调控中性粒细胞胞外诱捕网防治早产儿支气管肺发育不良的研究进展. 2026. doi: 10.12201/bmr.202604.00052

  陈志林, 文黛薇, 李明灯, 林琨峰. 基于网络药理学探讨小柴胡汤合瓜蒌薤白干预胃食管反流病伴胸闷的作用机制. 2025. doi: 10.12201/bmr.202511.00084

  李必波, 刘玮, 曹军, 张小梅, 王保华, 朱红青. 肝活血益肾方对代谢综合征相关勃起功能障碍患者临床效率和同型半胱氨酸、炎性因子和内皮功能影响. 2025. doi: 10.12201/bmr.202508.00012

  刘英超, 张丽娜, 张秋月, 李震, 田佳. 老年重症肺炎患者凝血功能指标变化及意义. 2024. doi: 10.12201/bmr.202411.00035

  代敏, 楼金成, 杨翠先, 陶鹏飞. 病原靶向测序在HIV合并肺部感染诊断中的应用. 2025. doi: 10.12201/bmr.202505.00050

  邵旭华, 陈志明, 魏杰, 许一帆, 李少华. t-P1NP/β-CTX与膝骨关节炎患者补肾壮骨汤疗效的相关性. 2025. doi: 10.12201/bmr.202501.00050

• 序号	提交日期	编号	操作
  1	2026-02-04	10.12201/bmr.202604.00088V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论