郑建宇. 跨尺度生命稳态视角下中医“形伤则肿”理论的现代重构. 2026. biomedRxiv.202603.00095
跨尺度生命稳态视角下中医“形伤则肿”理论的现代重构
DOI:10.12201/bmr.202603.00095
Modern Reconstruction of the TCM Theory "Physical Trauma Leads to Swelling" from a Cross-Scale Homeostatic Perspective
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摘要:中医“形伤则肿”理论阐述了形体结构损伤与水液代谢失常之间的内在联系,是中医经典病机理论的 重要组成部分,广泛应用于骨伤、痹病、水肿、疮疡等病证的临床诊疗中[1]。本文以形气学说为核 心,基于跨尺度生命稳态研究范式,从宏观形体、组织屏障、细胞结构及细胞外基质等多层次角 度,系统界定了“形”与“肿”的中医内涵及其现代生物学对应表征。研究梳理了“形伤—气失固摄—水 液失序—肿胀成形”的核心病机链条,并明确了该理论的适用范畴与边界条件,避免了概念泛化与循 环论证的问题。通过构建中西医融通的理论阐释框架,本研究揭示了结构损伤介导水液稳态失衡的 内在规律,为临床辨证区分形伤性肿胀与气失运化性肿胀提供了理论依据,同时推动了中医经典病 机理论的现代化、规范化与可检验化发展,为临床实践提供了更为精准的指导[1]。
Abstract: The traditional Chinese medicine (TCM) theory of "structural injury leading to swelling" elaborates on the internal relationship between structural damage and fluid metabolism disorders, and is an important part of the classic TCM pathogenesis theory. It is widely applied in the clinical diagnosis and treatment of bone injuries, arthralgia, edema, sores, and other diseases [1]. This paper takes the theory of form and qi as the core and systematically defines the TCM connotations of "form" and "swelling" and their corresponding modern biological characterizations from a multi - scale perspective, including the macro - form, tissue barriers, cell structure, and extracellular matrix, based on the research paradigm of cross - scale life homeostasis. The study combs the core pathogenesis chain of "structural injury - qi failing to consolidate - fluid disorder - swelling formation" and clarifies the applicable scope and boundary conditions of this theory, avoiding the problems of concept generalization and circular argumentation. By constructing a theoretical interpretation framework that integrates traditional Chinese and Western medicine, this study reveals the internal law of fluid homeostasis imbalance mediated by structural injury, provides a theoretical basis for clinical syndrome differentiation to distinguish between structural injury swelling and qi failure to transport and transform swelling, and at the same time promotes the modernization, standardization, and testability of the classic TCM pathogenesis theory, providing more accurate guidance for clinical practice [1].
Key words: Form injury leading to swelling; Cross - scale; Life homeostasis; Theory of form and qi; Reconstruction of traditional Chinese medicine theory提交时间:2026-04-14
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序号 提交日期 编号 操作 1 2026-03-21 10.12201/bmr.202603.00095V1
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