通讯作者: 吴建华, 491149402@qq.com

DOI：10.12201/bmr.202603.00093

Discussion on the Treatment of Knee Osteoarthritis from the Yangming System Combined with the Mechanism of the Gut-Joint Axis

• 摘要：目的:探讨从“阳明系统”论治膝骨关节炎的理论依据及治法。方法:分析现代医学“肠-关节轴”机制与中医“阳明系统”的内在联系,论证“阳明系统”角度上膝骨关节炎的病因病机及治法。结果:“肠-关节轴”中肠道菌群及其代谢产物通过调节炎症、免疫与骨代谢影响关节健康；中医“阳明系统”以脾胃、肠道为核心,主气血生化与输布,其功能失常导致膝骨关节炎发生；二者高度契合。结论:结合“肠-关节轴”机制,提出从“阳明系统”论治膝骨关节炎的新思路。

  关键词： 膝骨关节炎; “肠-关节轴”; “阳明系统”; 理论探讨

   

  Abstract: Objective: To explore the theoretical basis and therapeutic methods for the treatment of knee osteoarthritis from the Yangming system.Methods: The internal correlation between the modern medical mechanism of the gut-joint axis and the traditional Chinese medicine Yangming system was analyzed, and the etiology, pathogenesis and treatment principles of knee osteoarthritis from the perspective of the Yangming system were demonstrated.Results: In the gut-joint axis, intestinal flora and its metabolites affect joint health by regulating inflammation, immunity and bone metabolism. The Yangming system of traditional Chinese medicine takes the spleen, stomach and intestinal tract as the core, governing the production and distribution of qi and blood; its dysfunction leads to the occurrence of knee osteoarthritis. The two are highly consistent.Conclusion: Combined with the mechanism of the gut-joint axis, a new idea for the treatment of knee osteoarthritis from the Yangming system is proposed.

  Key words: Knee osteoarthritis; gut-joint axis; Yangming System; theoretical discussion

  提交时间：2026-03-20

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• 序号	提交日期	编号	操作
  1	2026-03-12	10.12201/bmr.202603.00093V1	下载

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