Discussion on the Treatment of Reflux Esophagitis Based on the Theory of Ascending and Descending of Qi Mechanism

Corresponding author: CHEN Yan, 45058301@qq.com

DOI: 10.12201/bmr.202507.00061

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  Abstract: Reflux esophagitis is a frequent form of the subtype of gastroesophageal reflux disease, which is characterized by the main symptoms of the heartburn and regurgitation. Traditional Chinese medicine has distinctive strengths in the treatment of this disease after a long period of clinical practice and rich experience. The doctrine of ascending and descending of Qi is one of the essential fundamental principles of traditional Chinese medicine. Traditional Chinese medicine considers that the onset of this syndrome is directly associated with the imbalance in the ascending and descending of Qi with human body. Clinically, the sickness is frequently caused by weakness of the spleen and stomach, discordance in which the liver and stomach are not in harmony, and congestion of the stomach Qi that goes upward and reverses the flow. The therapy is to invigorate the spleen and stomach, evacuate the liver and stomach, and comply to the ascending and descending of Qi. Based on the concept of ascending and descending of Qi, this essay explores the traditional Chinese medicine therapy of reflux esophagitis in terms of theoretical content, disease mechanism, and evidence therapy, with a view to providing reference and promotion for the treatment and research of reflux esophagitis.

  Key words: Reflux esophagitis; Gastro-esophageal reflux disease; Ascending and descending of Qi; Spleen and stomach; Liver and stomach

  Submit time: 18 July 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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