Advances in Breast-Conserving Surgery and Reconstruction Materials for Breast Cancer

Corresponding author: LiXuJun, 1044051835@qq.com

DOI: 10.12201/bmr.202610.00057

•  

  Abstract: Breast cancer is one of the major malignant tumors threatening women''s health. With the increasing popularity of breast-conserving surgery and rising patient demands for aesthetic outcomes, oncoplastic breast-conserving surgery (OBCS) has played a significant role in improving postoperative breast appearance through volume displacement and volume replacement. However, volume displacement relies heavily on the amount of residual breast tissue, while volume replacement increases surgical complexity and risks of donor site injury. Therefore, achieving minimally invasive and stable repair of breast defects remains an area warranting further exploration. In recent years, advances in tissue engineering materials and 3D printing have offered new perspectives for personalized reconstruction of post-lumpectomy cavities. This review summarizes current OBCS strategies, safety considerations, recent developments in tissue engineering, and challenges facing clinical translation, aiming to provide insights for clinical practice and future research.

  Key words: Breast cancer；Oncoplastic breast-conserving surgery；Oncological safety；tissue engineering materials

  Submit time: 26 October 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• Yao Genwu, Wang Yanwei, Guo Jinyi, Li Lulu, Dang Wenbo, Song Ailin. Advances in single-cell sequencing in the breast cancer. 2024. doi: 10.12201/bmr.202407.00053

  yuguozheng. Research Advances in Metadherin (MTDH) in Breast Cancer. 2026. doi: 10.12201/bmr.202601.00039

  邹雪宜, Ju shuyv, Chen min, Rui jiamin, Li shihua, Cui shuna. Risk factors of endometrial lesions detected in patients taking tamoxifen after breast cancer surgery. 2025. doi: 10.12201/bmr.202512.00077

  ma guang fan, chen xiao zhen, zhou sen. Effect of esketamine on early postoperative mental state in patients with breast cancer. 2024. doi: 10.12201/bmr.202412.00054

  鲍呈洋, yangyingtao. Factors Influencing the Efficacy of Neoadjuvant Chemotherapy in HER2-Negative Breast Cancer. 2025. doi: 10.12201/bmr.202511.00048

  ZHOU Zhisheng¹, CHEN Jintao¹, XU Xuemei¹, ZHU Jing¹. Trans-pQTL analysis for the causal association between layilin and breast cancer. 2026. doi: 10.12201/bmr.202606.00067

  qianlin, yangyi. Analysis the Medication Regularity of TCM in the Treatment of Breast Cancer in the Real World Based on Data Mining Method. 2025. doi: 10.12201/bmr.202506.00022

  李媛, baihong, luxue, xuyan, chenye. Study on the current status and influencing factors of cognition and attitudes toward advance care planning among breast cancer patients. 2026. doi: 10.12201/bmr.202603.00049

  李威, Geng Zhong li, Angshaer·Sulaiman. Innovation and evolution of neural monitoring technology in endoscopic thyroid cancer surgery. 2024. doi: 10.12201/bmr.202411.00051

  duanshiya, Li Juan, LI Linpei. Treatment Based on Syndrome Differentiation of the Pre-metastatic Niche in Breast Cancer Liver Metastasis from the Perspective of “Liver is Yin in Form and Yang in Function. 2026. doi: 10.12201/bmr.202609.00027

• ID	Submit time	Number	Download
  1	2026-09-13	10.12201/bmr.202610.00057V1	Download

• Public  Anonymous  To author only Submit Comments