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Corresponding author: zhoujing, 1264933245@qq.com

DOI: 10.12201/bmr.202603.00042

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  Abstract: 【Abstract】Objective :To understand the authentic medication experiences and perceptions of patients with gout, explore the facilitating factors and barriers affecting medication adherence, and provide a reference for the development of targeted medication management strategies. Methods: Using purposive sampling, 16 patients with gout hospitalized in the Department of Rheumatology and Immunology at the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from June 2025 to September 2025 were selected for in-depth interviews. Interview data were analyzed using NVivo 11.0 software, and themes were extracted based on the COM-B model as the theoretical framework. Results: Seven sub-themes related to barriers were identified: insufficient disease and medication knowledge, adverse drug reactions, reduced patient capability, inadequate social support, poor economic conditions and high costs of accessing medical resources, low medication adherence confidence, and low perceived medication benefits. Four sub-themes related to facilitating factors were identified: structured medication habits, adequate social support, patient-physician trust and treatment confidence, and disease severity with perceived consequences. Conclusion: The factors influencing medication adherence in patients with gout are multidimensional. Healthcare professionals should provide personalized health education tailored to the specific reasons for poor medication adherence in individual patients.

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  Submit time: 11 March 2026

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2025-12-25	10.12201/bmr.202603.00042V1	Download

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